Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386526 | 0.94 | MAPT (0.60) | MAPTKDM4EALDH1A1GAATP53 | |
| SCHEMBL20740118 | 0.94 | MAPT (0.60) | MAPTKDM4EALDH1A1GAATP53 | |
| SCHEMBL28996853 | 0.93 | MAPT (0.60) | MAPTKDM4EALDH1A1GAATP53 | |
| SCHEMBL28518373 | 0.91 | MAPT (0.58) | MAPTKDM4EALDH1A1GAATP53 | |
| SCHEMBL28702242 | 0.89 | MAPT (0.60) | MAPTKDM4EALDH1A1GAATP53 | |
| SCHEMBL30050183 | 0.88 | MAPT (0.65) | MAPTKDM4EALDH1A1GAATP53 | |
| SCHEMBL30049710 | 0.86 | MAPT (0.56) | MAPTKDM4EALDH1A1GAATP53 | |
| SCHEMBL8009070 | 0.85 | KDM4E (0.87) | MAPTKDM4EALDH1A1GAATP53 | |
| SCHEMBL28657635 | 0.84 | MAPT (0.62) | MAPTKDM4EALDH1A1GAATP53 | |
| SCHEMBL28121912 | 0.83 | TUBB4A (0.65) | MAPTKDM4ETP53CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279653-A | Compounds for the treatment of ocular diseases and disorders | 以色列国家农业和农村发展农业研究组织沃尔坎尼中心 | 2023-12-22 | — | — | CN | claimed |
| CN-106102757-B | Anti-neuritis and protective compounds in yarrow | 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 | 2021-06-25 | — | — | CN | claimed |
| CN-118176008-A | Pelargonium graveolens extract for treating traumatic brain injury | 以色列国家农业与农村发展部农业研究组织（ARO）（Volciti 中心） | 2024-06-11 | — | — | CN | disclosed |
| CN-117279653-A | Compounds for the treatment of ocular diseases and disorders | 以色列国家农业和农村发展农业研究组织沃尔坎尼中心 | 2023-12-22 | — | — | CN | disclosed |
| CN-117279653-A | Compounds for the treatment of ocular diseases and disorders | 以色列国家农业和农村发展农业研究组织沃尔坎尼中心 | 2023-12-22 | — | — | CN | disclosed |
| CN-106102757-B | Anti-neuritis and protective compounds in yarrow | 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 | 2021-06-25 | — | — | CN | disclosed |
| CN-106102757-A | Neuritis and protectiveness compound in the Achillea ageratum of pole | 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 | 2016-11-09 | — | — | CN | disclosed |