SCHEMBL28657635

SCHEMBL28657635

COc1cccc(-c2oc3c(OC)c(OC)c(O)c(O)c3c(=O)c2OC)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.62
KDM4E B2RXH2 3/20 0.62
GAA P10253 2/20 0.62
TUBB4A P04350 2/20 0.61
TUBB P07437 2/20 0.61
TUBA3C P0DPH7 2/20 0.61
TUBA1B P68363 2/20 0.61
TUBA4A P68366 2/20 0.61
TUBB4B P68371 2/20 0.61
TUBB3 Q13509 2/20 0.61
TUBB2A Q13885 2/20 0.61
TUBB8 Q3ZCM7 2/20 0.61
TUBA3E Q6PEY2 2/20 0.61
TUBA1A Q71U36 2/20 0.61
TUBA1C Q9BQE3 2/20 0.61
TUBB6 Q9BUF5 2/20 0.61
TUBB2B Q9BVA1 2/20 0.61
TUBB1 Q9H4B7 2/20 0.61
ALDH1A1 P00352 1/20 0.57
TP53 P04637 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28996853 0.91 MAPT (0.60) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL30049710 0.88 MAPT (0.56) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL28702242 0.88 MAPT (0.60) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL29134048 0.85 MAPT (0.64) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL2216677 0.84 KDM4E (0.70) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL28080467 0.84 MAPT (0.65) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL30050183 0.84 MAPT (0.65) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL29386526 0.83 MAPT (0.60) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL28518373 0.83 MAPT (0.58) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL20740118 0.83 MAPT (0.60) MAPTKDM4EGAATUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117398431-A Application of citrus unshiu extract in preparation of medicine for preventing and/or treating alcoholic liver injury 浙江大学 2024-01-16 CN claimed
CN-117398431-A Application of citrus unshiu extract in preparation of medicine for preventing and/or treating alcoholic liver injury 浙江大学 2024-01-16 CN disclosed
CN-109876088-B Natural hypoglycemic preparation capable of lowering blood sugar by regulating intestinal flora balance 浙江农林大学暨阳学院 2021-11-16 CN disclosed