Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28262113 | 0.82 | KDM4E (0.39) | KDM4EGPR3AKT1 | |
| SCHEMBL378548 | 0.82 | KDM4E (0.39) | KDM4EGPR3AKT1 | |
| SCHEMBL27619538 | 0.81 | KDM4E (0.38) | KDM4EGPR3AKT1 | |
| SCHEMBL29176096 | 0.81 | KDM4E (0.38) | KDM4EGPR3AKT1 | |
| SCHEMBL27619154 | 0.81 | KDM4E (0.38) | KDM4EGPR3AKT1 | |
| SCHEMBL28080659 | 0.77 | KDM4E (0.35) | KDM4EGPR3AKT1 | |
| SCHEMBL28258357 | 0.77 | KDM4E (0.35) | KDM4EGPR3AKT1 | |
| SCHEMBL31277019 | 0.73 | ALDH1A1 (0.38) | KDM4EGPR3AKT1 | |
| SCHEMBL27971102 | 0.73 | ALDH1A1 (0.33) | KDM4EGPR3 | |
| SCHEMBL29636355 | 0.71 | CES1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105859621-A | Difluoromethylene phenanthridine derivative and preparation method thereof | 上海大学 | 2016-08-17 | — | — | CN | claimed |
| CN-105859621-A | Difluoromethylene phenanthridine derivative and preparation method thereof | 上海大学 | 2016-08-17 | — | — | CN | disclosed |