Phenol

Phenol

SCHEMBL28080984

Oc1ccccc1.[CH2]C(=O)c1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.56
CA2 P00918 5/20 0.55
CA12 O43570 4/20 0.55
CA1 P00915 4/20 0.55
CA9 Q16790 4/20 0.55
TDP1 Q9NUW8 4/20 0.55
CA4 P22748 4/20 0.55
CA3 P07451 3/20 0.55
CA14 Q9ULX7 3/20 0.55
GLA P06280 1/20 0.55
MAPT P10636 3/20 0.50
CYP3A4 P08684 3/20 0.50
KMT2A Q03164 3/20 0.50
TSHR P16473 2/20 0.50
PARP1 P09874 2/20 0.50
RAB9A P51151 2/20 0.50
MEN1 O00255 2/20 0.50
LMNA P02545 2/20 0.50
POLB P06746 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL736 0.89
SCHEMBL80529 0.81 MAPT (0.60) CES2CA2CA12CA1CA9
Benzamide SCHEMBL1785440 0.80 PARP1 (0.80) CES2CA2CA12CA1CA9
Benzophenone SCHEMBL28197225 0.80 ALDH1A1 (0.70) CES2CA2CA12CA1CA9
SCHEMBL28126175 0.80 ALDH1A1 (0.70) CES2TDP1MAPTCYP3A4KMT2A
Benzamide SCHEMBL9619649 0.80 PARP1 (0.80) CES2CA2CA12CA1CA9
Benzoic Acid SCHEMBL25410474 0.79 TSHR (0.78) CES2CA2CA12CA1CA9
Benzoic Acid SCHEMBL10630775 0.79 TSHR (0.78) CES2CA2CA12CA1CA9
Benzoic Acid SCHEMBL484290 0.79 TSHR (0.78) CES2CA2CA12CA1CA9
Benzophenone SCHEMBL5071338 0.79 ALDH1A1 (0.78) CES2CA2CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104379628-B Sulfonium compound, it prepares and application thereof 巴斯夫欧洲公司 2016-11-16 CN disclosed