Dimethylformamide

Dimethylformamide

SCHEMBL28081050

CN(C)C=O.F.F.Fc1ccccc1Cl

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 6/20 0.39
TDP1 Q9NUW8 2/20 0.37
KCNH2 Q12809 2/20 0.36
CYP11B2 P19099 4/20 0.36
TSHR P16473 2/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dichlorobenzene SCHEMBL28124693 0.83 TSHR (0.53) CYP11B1TDP1TSHRMEN1KMT2A
SCHEMBL27603108 0.81 LMNA (0.43) TDP1TSHRMEN1KMT2AALDH1A1
Fluoride SCHEMBL19837704 0.80 TSHR (0.53) TSHRMEN1KMT2AALDH1A1GAA
Fluoride SCHEMBL8966802 0.80 TSHR (0.53) TSHRMEN1KMT2AALDH1A1GAA
Formamide SCHEMBL29215178 0.79 TAAR1 (0.42) TDP1TSHRMEN1KMT2AALDH1A1
Propionaldehyde SCHEMBL28014514 0.78 MEN1 (0.39) TDP1TSHRMEN1KMT2AALDH1A1
SCHEMBL168042 0.78
SCHEMBL29591443 0.78
Nitrogen SCHEMBL9740678 0.75 TSHR (0.47) TDP1TSHRMEN1KMT2AALDH1A1
Methylamine SCHEMBL27811456 0.75 TAAR1 (0.52) TDP1TSHRMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105793387-A Composition containing a polymeric binder comprising acrylate and/or methacrylate units 默克专利有限公司 2016-07-20 CN disclosed