Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Caffeic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.73 |
| ▸ | GAA | P10253 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | MMP1 | P03956 | 3/20 | 0.73 |
| ▸ | MMP2 | P08253 | 3/20 | 0.73 |
| ▸ | MMP9 | P14780 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | CA12 | O43570 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | CA1 | P00915 | 2/20 | 0.73 |
| ▸ | CA2 | P00918 | 2/20 | 0.73 |
| ▸ | CA4 | P22748 | 2/20 | 0.73 |
| ▸ | CA6 | P23280 | 2/20 | 0.73 |
| ▸ | CA7 | P43166 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Caffeic Acid SCHEMBL28081170 | 1.00 | KDM4E (0.73) | KDM4EMAPTPTPN1GAAKMT2A | |
| Caffeic Acid SCHEMBL15971329 | 0.91 | KDM4E (0.89) | KDM4EMAPTPTPN1GAAKMT2A | |
| Caffeic Acid SCHEMBL28110813 | 0.87 | KDM4E (0.96) | KDM4EMAPTPTPN1GAAKMT2A | |
| Caffeic Acid SCHEMBL28110812 | 0.87 | KDM4E (0.96) | KDM4EMAPTPTPN1GAAKMT2A | |
| Caffeic Acid SCHEMBL3682144 | 0.85 | KDM4E (1.00) | KDM4EMAPTPTPN1GAAKMT2A | |
| Caffeic Acid SCHEMBL29447135 | 0.85 | KDM4E (1.00) | KDM4EMAPTPTPN1GAAKMT2A | |
| Caffeic Acid SCHEMBL30050844 | 0.85 | KDM4E (1.00) | KDM4EMAPTPTPN1GAAKMT2A | |
| Caffeic Acid SCHEMBL7064846 | 0.85 | KDM4E (1.00) | KDM4EMAPTPTPN1GAAKMT2A | |
| Caffeic Acid SCHEMBL21114743 | 0.85 | KDM4E (1.00) | KDM4EMAPTPTPN1GAAKMT2A | |
| Caffeic Acid SCHEMBL29353048 | 0.85 | KDM4E (1.00) | KDM4EMAPTPTPN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108472210-A | Composition based on the water phase containing water-free composite material dispersion | 欧莱雅 | 2018-08-31 | — | — | CN | disclosed |
| CN-107982077-A | Cosmetic composition comprising silica aerogel particles and clay | 莱雅公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-107028798-A | Cosmetic composition comprising high water absorbency polymer and organic uv filter | 莱雅公司 | 2017-08-11 | — | — | CN | disclosed |
| CN-101926744-B | Cosmetic composition comprising a superabsorbent polymer and an organic UV sunscreen | 莱雅公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-105722496-A | Fatty acid esters or liquid alkylpolyglucosides containing sugars with HLB <8 and C8-C18Two-phase compositions of branched alkanes | 莱雅公司 | 2016-06-29 | — | — | CN | disclosed |