Caffeic Acid

Caffeic Acid

SCHEMBL29447135

O=C(O)/C=C\c1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 1.00
HSD17B10 Q99714 3/20 1.00
CA12 O43570 3/20 1.00
CA1 P00915 3/20 1.00
CA2 P00918 3/20 1.00
CA3 P07451 3/20 1.00
CA4 P22748 3/20 1.00
CA6 P23280 3/20 1.00
CA5A P35218 3/20 1.00
CA7 P43166 3/20 1.00
CA9 Q16790 3/20 1.00
CA14 Q9ULX7 3/20 1.00
CA5B Q9Y2D0 3/20 1.00
MAPT P10636 2/20 1.00
TTR P02766 2/20 1.00
APP P05067 2/20 1.00
AKR1B10 O60218 2/20 1.00
AKR1B1 P15121 2/20 1.00
DPP4 P27487 2/20 1.00
MMP1 P03956 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Caffeic Acid SCHEMBL23359 1.00 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL30501140 1.00 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL30050844 1.00 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL29353048 1.00 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL3682144 1.00 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL7064846 1.00 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL23358 1.00 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL1262229 1.00 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL21114743 1.00 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL9477189 0.98 KDM4E (0.96) KDM4EHSD17B10CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118203613-A Preparation for treating bacterial mastitis, preparation method and application 扬州大学 2024-06-18 CN claimed
US-20220402833-A1 Nutritional Compositions for Plants and Soils ENVIROKURE, INCORPORATED (US) 2022-12-22 US claimed
CN-119837805-A Sweet potato leaf whitening cream and preparation method thereof 海南大学三亚南繁研究院 2025-04-18 CN disclosed
US-20250002496-A1 INDOLE DERIVATIVES AS A MATRIX DESIGN FRAMEWORK FOR MALDI MASS SPECTROMETRY WITH BROAD APPLICATIONS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA 2025-01-02 US disclosed
CN-116636460-B Ningxia wolfberry callus induction culture medium with high antioxidant activity and induction method 江南大学 2024-08-06 CN disclosed
EP-4346810-A1 COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF Unigen, Inc. (US) 2024-04-10 EP disclosed
CN-117547562-A An anti-inflammatory herba Saxifragae extract, and its preparation method and application 北京农学院 2024-02-13 CN disclosed
CN-116636460-A Ningxia wolfberry callus induction culture medium with high antioxidant activity and induction method 江南大学 2023-08-25 CN disclosed
US-20230255989-A1 GLYCAN COMPOSITIONS AND USES THEREOF DSM NUTRITIONAL PRODUCTS LLC (US) 2023-08-17 US disclosed
CN-113200903-B Pyrrole alkaloid compound with antifeedant and defensive functions on coccinella twenty-eight star in Solanum septemlobum and separation and extraction method thereof 沈阳农业大学 2023-04-25 CN disclosed
US-20220402833-A1 Nutritional Compositions for Plants and Soils ENVIROKURE, INCORPORATED (US) 2022-12-22 US disclosed
WO-2022256624-A1 COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF UNIGEN, INC. (US) 2022-12-08 WO disclosed
US-20220387366-A1 Compositions for Regulating Homeostasis of Cortisol and Improving Sleep Quality and Methods of Use and Production Thereof UNIGEN, INC. (US) 2022-12-08 US disclosed
US-11299437-B2 Nutritional compositions for plants and soils EnviroKure, Inc. (US) 2022-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002496-A1 INDOLE DERIVATIVES AS A MATRIX DESIGN FRAMEWORK FOR MALDI MASS SPECTROMETRY WITH BROAD APPLICATIONS IDO1, IDO2, AANAT KDM4E 1712/4885HSD17B10 1656/4885CA12 757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.