Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29058735 | 0.83 | NPSR1 (0.44) | TSHRSCN9AHTTPIM1CYP3A4 | |
| SCHEMBL28629411 | 0.78 | PARP1 (0.42) | TSHRSCN9APIM1CYP3A4 | |
| SCHEMBL29133996 | 0.76 | ALDH1A1 (0.44) | TSHRGAAPIM1LMNACYP1A2 | |
| SCHEMBL5633185 | 0.76 | F7 (0.52) | F7F3SARM1SIRT2SIRT6 | |
| Pyridine Dicarboxamide SCHEMBL29587789 | 0.73 | TSHR (0.59) | TSHRSCN9APIM1LMNACYP1A2 | |
| Pyridine Dicarboxamide SCHEMBL229425 | 0.73 | TSHR (0.59) | TSHRSCN9APIM1LMNACYP1A2 | |
| SCHEMBL29505512 | 0.72 | SCN9A (0.59) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL28324757 | 0.72 | SCN9A (0.59) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL17591716 | 0.71 | HTT (0.56) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL1648430 | 0.71 | KCNA5 (0.47) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732672-A | Novel double-core functional complex and preparation method | 河南工程学院 | 2016-07-06 | — | — | CN | disclosed |