Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | FABP3 | P05413 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL2569824 | 0.93 | CA1 (0.62) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Butyric Acid SCHEMBL5172257 | 0.93 | FFAR3 (0.64) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Dodecanoate SCHEMBL394257 | 0.89 | FABP3 (0.60) | CA1CES2CES1FABP3NFKB1 | |
| Stearic Acid SCHEMBL8401965 | 0.89 | FABP3 (0.60) | CA1CES2CES1FABP3NFKB1 | |
| Octanoic Acid SCHEMBL5171291 | 0.89 | FABP3 (0.60) | CA1CES2CES1FABP3NFKB1 | |
| Palmitic Acid SCHEMBL27958546 | 0.89 | FABP3 (0.60) | CA1CES2CES1FABP3NFKB1 | |
| Propionic Acid SCHEMBL9716508 | 0.88 | CA1 (0.48) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Bicarbonate SCHEMBL8729890 | 0.87 | CA1 (0.46) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Dodecanoate SCHEMBL10558070 | 0.87 | FABP3 (0.58) | CA1CES2CES1FABP3NFKB1 | |
| Dodecanoate SCHEMBL1115521 | 0.87 | FABP3 (0.58) | CA1CES2CES1FABP3NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698097-A | TRI-BUTYL TIN LINOLEATE, SUCCINATE, BENZOATE, OR SALICYLATE | EMA COMPANY (US) | 1987-10-06 | — | — | US | claimed |
| US-4661400-A | TRI-N-BUTYL TIN ESTER AND CLAY FILLER | EMA COMPANY (US) | 1987-04-28 | — | — | US | claimed |
| US-4555356-A | CONTAINS A TRIBUTYL TIN ESTER | EMA COMPANY (US) | 1985-11-26 | — | — | US | claimed |
| US-4554092-A | TRIBUTYLTIN CARBOXYLATE | EMA COMPANY (US) | 1985-11-19 | — | — | US | claimed |
| US-20250024837-A1 | PESTICIDE SYSTEM | BANISH, MICHELE | 2025-01-23 | — | — | US | disclosed |
| US-20240074434-A1 | COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE | ROBBINS JEFFREY HANSON (US) | 2024-03-07 | — | — | US | disclosed |
| US-20240065262-A1 | COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE | ROBBINS JEFFREY HANSON (US) | 2024-02-29 | — | — | US | disclosed |
| WO-2023154183-A1 | COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE | ROBBINS JEFFREY (US) | 2023-08-17 | — | — | WO | disclosed |
| US-20230172194-A1 | COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE | ROBBINS JEFFREY HANSON (US) | 2023-06-08 | — | — | US | disclosed |
| US-20220272987-A1 | COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE | ROBBINS JEFFREY H (US) | 2022-09-01 | — | — | US | disclosed |
| EP-2207416-B1 | ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM | IMERYS FILTRATION MINERALS INC (US) | 2018-11-07 | — | — | EP | disclosed |
| US-20100239679-A1 | ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM | WORLD MINERALS, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| US-4661400-A | TRI-N-BUTYL TIN ESTER AND CLAY FILLER | EMA COMPANY (US) | 1987-04-28 | — | — | US | disclosed |
| US-4555356-A | CONTAINS A TRIBUTYL TIN ESTER | EMA COMPANY (US) | 1985-11-26 | — | — | US | disclosed |
| US-4555356-A | CONTAINS A TRIBUTYL TIN ESTER | EMA COMPANY (US) | 1985-11-26 | — | — | US | disclosed |
| US-4554092-A | TRIBUTYLTIN CARBOXYLATE | EMA COMPANY (US) | 1985-11-19 | — | — | US | disclosed |
| US-4554092-A | TRIBUTYLTIN CARBOXYLATE | EMA COMPANY (US) | 1985-11-19 | — | — | US | disclosed |
| US-4482759-A | Fungicidally active benzhydrol derivatives | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-11-13 | — | — | US | disclosed |
| US-4324799-A | Fungicidal thioglycolic acid anilides, processes for their manufacture and pesticidal compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | disclosed |
| US-3997461-A | TRIALKYLTIN CARBOXYLATE | PORTER PAINT CO. (US) | 1976-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250024837-A1 | PESTICIDE SYSTEM | ACHE, PFAS, FPGS | CA1 1542/4885FFAR3 452/4885HDAC3 3219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.