Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL27908760 | 0.79 | TSHR (0.41) | NAPRTMAPTMEN1KMT2AALDH1A1 | |
| Isonicotinic Acid SCHEMBL3908497 | 0.77 | NAPRT (0.90) | NAPRTKDM4CMAPTMEN1KMT2A | |
| Isonicotinic Acid SCHEMBL1108 | 0.77 | — | — | |
| Isonicotinic Acid SCHEMBL1414914 | 0.77 | NAPRT (1.00) | NAPRTKDM4CMAPTMEN1KMT2A | |
| Isonicotinic Acid SCHEMBL28136907 | 0.76 | NAPRT (0.71) | NAPRTMEN1KMT2AALDH1A1CYP2D6 | |
| Isonicotinic Acid SCHEMBL28323540 | 0.75 | NAPRT (0.85) | NAPRTKDM4CMAPTMEN1KMT2A | |
| Isonicotinic Acid SCHEMBL28533400 | 0.75 | NAPRT (0.85) | NAPRTKDM4CMAPTMEN1KMT2A | |
| Isonicotinic Acid SCHEMBL8358038 | 0.75 | NAPRT (0.85) | NAPRTKDM4CMEN1KMT2AALDH1A1 | |
| Isonicotinic Acid SCHEMBL25219686 | 0.74 | NAPRT (0.94) | NAPRTKDM4CMAPTMEN1KMT2A | |
| Isonicotinic Acid SCHEMBL25261208 | 0.74 | NAPRT (0.94) | NAPRTKDM4CMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105906561-A | Preparation method of 2-aminopyridine-4-methanol medical intermediate | 苏州艾缇克药物化学有限公司 | 2016-08-31 | — | — | CN | disclosed |