Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.52 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29828855 | 0.87 | NAPRT (0.59) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| Isonicotinic Acid SCHEMBL1108 | 0.84 | — | — | |
| Isonicotinic Acid SCHEMBL1414914 | 0.84 | NAPRT (1.00) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| Benzoic Acid SCHEMBL11512189 | 0.82 | TSHR (0.70) | NAPRTKMT2AMEN1ALDH1A1CYP3A4 | |
| Isonicotinic Acid SCHEMBL8358038 | 0.82 | NAPRT (0.85) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| Isonicotinic Acid SCHEMBL25222705 | 0.82 | NAPRT (0.94) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| Isonicotinic Acid SCHEMBL25261208 | 0.82 | NAPRT (0.94) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| Isonicotinic Acid SCHEMBL25271512 | 0.82 | NAPRT (0.94) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| Isonicotinic Acid SCHEMBL25269381 | 0.82 | NAPRT (0.94) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| Isonicotinic Acid SCHEMBL1025948 | 0.82 | NAPRT (0.94) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105026372-B | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2018-06-05 | — | — | CN | disclosed |
| CN-104220422-B | EP1 receptors ligands | 埃斯特韦实验室有限公司 | 2017-11-07 | — | — | CN | disclosed |
| CN-107108613-A | Bu Luomo domain inhibitor and application thereof | 基因泰克公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-104812755-B | It is used as the pyrazolo pyridine derivatives of TTX S blocking agents | 拉夸里亚创药株式会社 | 2017-08-08 | — | — | CN | disclosed |
| CN-106660982-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2017-05-10 | — | — | CN | disclosed |