Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 4/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19650807 | 0.90 | LOXL2 (0.57) | LOXL2KDM1ASLC6A4MAOAMAOB | |
| Trifluoroacetic Acid SCHEMBL5014957 | 0.87 | SLC6A2 (0.43) | KDM1ASLC6A2SLC6A4MAOAMAOB | |
| SCHEMBL11432052 | 0.86 | HRH3 (0.62) | LOXL2KDM1AMAOAMAOBHRH3 | |
| SCHEMBL2579002 | 0.85 | HRH3 (0.66) | LOXL2KDM1AMAOAMAOBHRH3 | |
| SCHEMBL28081753 | 0.81 | KDM1A (0.54) | KDM1ASLC6A2SLC6A4MAOAMAOB | |
| SCHEMBL24093028 | 0.80 | LOXL2 (0.46) | LOXL2KDM1ASLC6A4MAOAMAOB | |
| SCHEMBL23514564 | 0.80 | LOXL2 (0.46) | LOXL2KDM1ASLC6A4MAOAMAOB | |
| SCHEMBL1586716 | 0.79 | HRH3 (0.49) | SLC6A2SLC6A4HRH3MEN1RAB9A | |
| SCHEMBL3355681 | 0.79 | BCHE (0.54) | KDM1ASLC6A2SLC6A4MAOAMAOB | |
| SCHEMBL24392683 | 0.79 | HRH3 (0.49) | SLC6A2SLC6A4HRH3MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103201267-B | AMPK-activating heterocyclic compounds and methods of use thereof | 里格尔药品股份有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-104016977-B | A kind of replacement thiadiazine diketone derivative and preparation method thereof and application | 山东大学 | 2016-06-22 | — | — | CN | disclosed |