Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28134988 | 0.83 | SLC18A3 (0.60) | SLC18A3HSD11B1MGLL | |
| SCHEMBL16632062 | 0.83 | STS (0.51) | — | |
| SCHEMBL27968804 | 0.82 | HSD11B1 (0.56) | HSD11B1MGLL | |
| SCHEMBL997113 | 0.81 | CNR2 (0.43) | SLC18A3HRH3CNR2HSD11B1USP30 | |
| SCHEMBL16632026 | 0.81 | HSD11B1 (0.46) | HRH3HSD11B1MGLLDPP4 | |
| SCHEMBL16632109 | 0.79 | HSD11B1 (0.47) | HRH3CNR2HSD11B1LIPEMGLL | |
| SCHEMBL27758338 | 0.79 | HSD11B1 (0.57) | HSD11B1MGLL | |
| SCHEMBL28081872 | 0.78 | PIK3CD (0.46) | HRH3HSD11B1LIPEMGLLDPP4 | |
| SCHEMBL27968916 | 0.77 | HSD11B1 (0.60) | HSD11B1MGLL | |
| SCHEMBL27991279 | 0.76 | MGLL (0.51) | SLC18A3HSD11B1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829294-A | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | 詹森药业有限公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-105829295-A | Phenyl Linked Quinolinyl Modulators Of Ror-Gamma-T | 詹森药业有限公司 | 2016-08-03 | — | — | CN | disclosed |