Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28832324 | 0.94 | TDP1 (0.49) | TP53MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL28081968 | 0.91 | MAPT (0.49) | TP53MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL28082011 | 0.90 | TDP1 (0.51) | MAPTKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL28081953 | 0.88 | TDP1 (0.48) | TDP1PYGLNHERF1 | |
| SCHEMBL28257814 | 0.84 | TDP1 (0.51) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL28081958 | 0.84 | EGFR (0.51) | KMT2AALDH1A1MEN1TDP1PYGL | |
| SCHEMBL28081980 | 0.84 | TP53 (0.69) | TP53MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL28081982 | 0.83 | PYGL (0.56) | TP53MAPTKMT2AMEN1LMNA | |
| SCHEMBL28257737 | 0.83 | TDP1 (0.47) | TP53MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL22983913 | 0.78 | MAPT (0.61) | MAPTKMT2AALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105820104-B | A kind of indoles -2- amides compound with anti-inflammatory effect and its application in preparing anti-inflammatory drugs | 温州医科大学 | 2018-12-11 | — | — | CN | disclosed |
| CN-105820104-A | Indole-2-acetamide compound with anti-inflammatory effect, and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2016-08-03 | — | — | CN | disclosed |