Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.47 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.47 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 3/20 | 0.46 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.46 |
| ▸ | PYGL | P06737 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28081958 | 0.91 | EGFR (0.51) | TDP1MEN1KMT2AALDH1A1NHERF1 | |
| SCHEMBL28082017 | 0.90 | TP53 (0.50) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28081953 | 0.90 | TDP1 (0.48) | TDP1NHERF1PYGL | |
| SCHEMBL28257814 | 0.89 | TDP1 (0.51) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28081968 | 0.89 | MAPT (0.49) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28832324 | 0.89 | TDP1 (0.49) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28257737 | 0.84 | TDP1 (0.47) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28081982 | 0.81 | PYGL (0.56) | MEN1KMT2AMAPTLMNANHERF1 | |
| SCHEMBL6019366 | 0.79 | POLB (0.64) | MEN1KMT2AMAPTLMNACYP19A1 | |
| SCHEMBL931628 | 0.77 | NHERF1 (0.52) | MEN1KMT2ALMNACYP19A1NHERF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105820104-B | A kind of indoles -2- amides compound with anti-inflammatory effect and its application in preparing anti-inflammatory drugs | 温州医科大学 | 2018-12-11 | — | — | CN | disclosed |
| CN-105820104-A | Indole-2-acetamide compound with anti-inflammatory effect, and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2016-08-03 | — | — | CN | disclosed |