Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28082036 | 0.86 | NPC1 (0.64) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL28081972 | 0.83 | KDM4E (0.72) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL28081980 | 0.82 | TP53 (0.69) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL1415543 | 0.81 | POLB (0.58) | MAPTKDM4EALDH1A1HDAC3HDAC1 | |
| SCHEMBL27908704 | 0.81 | PLCG2 (0.61) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL28788142 | 0.80 | KDM4E (0.52) | MAPTKDM4EALDH1A1HDAC3HDAC4 | |
| SCHEMBL10064737 | 0.78 | HRH4 (0.49) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL28082017 | 0.76 | TP53 (0.50) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL28081990 | 0.75 | KDM4E (0.63) | MAPTKDM4ERAB9ANPC1KMT2A | |
| SCHEMBL12501305 | 0.75 | HRH4 (0.58) | MAPTKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105820104-B | A kind of indoles -2- amides compound with anti-inflammatory effect and its application in preparing anti-inflammatory drugs | 温州医科大学 | 2018-12-11 | — | — | CN | disclosed |
| CN-105820104-A | Indole-2-acetamide compound with anti-inflammatory effect, and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2016-08-03 | — | — | CN | disclosed |