Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960044 | 0.78 | — | — | |
| SCHEMBL360568 | 0.78 | — | — | |
| Ethoxycarbonyl Group SCHEMBL30844535 | 0.74 | CA12 (0.36) | LMNA | |
| Ethoxycarbonyl Group SCHEMBL27884564 | 0.74 | CA12 (0.36) | LMNA | |
| Ethoxycarbonyl Group SCHEMBL27868253 | 0.74 | ALDH1A1 (0.36) | LMNA | |
| SCHEMBL28068465 | 0.71 | — | — | |
| Ethoxycarbonyl Group SCHEMBL27732876 | 0.71 | LMNA (0.36) | LMNA | |
| Ethoxycarbonyl Group SCHEMBL27729726 | 0.70 | LMNA (0.32) | LMNA | |
| Ethoxycarbonyl Group SCHEMBL27710452 | 0.69 | MEN1 (0.44) | LMNA | |
| SCHEMBL29234117 | 0.67 | CYP17A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814054-A | Fused imidazole and pyrazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |