Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 4/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19107153 | 0.84 | EPHX2 (0.55) | EPHX2HTR6HTR2CPLD1KDM4E | |
| SCHEMBL6111507 | 0.81 | EPHX2 (0.52) | EPHX2HTR2CPLD1KDM4EALDH1A1 | |
| SCHEMBL19853561 | 0.79 | EPHX2 (0.50) | EPHX2HTR2CPLD1 | |
| SCHEMBL28070943 | 0.78 | DRD4 (0.53) | EPHX2HTR6HTR2CPLD1KDM4E | |
| SCHEMBL9078264 | 0.78 | EPHX2 (0.49) | EPHX2HTR2CPLD1KDM4EALDH1A1 | |
| SCHEMBL18842836 | 0.77 | EPHX2 (0.48) | EPHX2HTR2CPLD1 | |
| SCHEMBL28071072 | 0.75 | EPHX2 (0.56) | EPHX2HTR2CPLD1KDM4EALDH1A1 | |
| SCHEMBL4807185 | 0.75 | EPHX2 (0.49) | EPHX2HTR2C | |
| Piperazine SCHEMBL6684567 | 0.74 | EPHX2 (0.48) | EPHX2HTR2C | |
| SCHEMBL27880538 | 0.74 | EPHX2 (0.45) | EPHX2HTR6HTR2CPLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814054-A | Fused imidazole and pyrazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |