SCHEMBL2808264

SCHEMBL2808264

CC(C)OC(=O)CCC(=O)O.CCCC[Sn](CCCC)CCCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.56
AKR1B1 P15121 1/20 0.39
GPR84 Q9NQS5 7/20 0.38
PPARG P37231 7/20 0.38
PPARD Q03181 7/20 0.38
PPARA Q07869 7/20 0.38
HDAC11 Q96DB2 5/20 0.38
TSHR P16473 4/20 0.38
PTPN1 P18031 3/20 0.38
ALDH1A1 P00352 2/20 0.38
TLR2 O60603 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
FABP4 P15090 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
ESR1 P03372 1/20 0.38
ALOX15 P16050 1/20 0.38
PDE4A P27815 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL2855880 0.84 LMNA (0.59) LMNAAKR1B1GPR84PPARGPPARD
SCHEMBL191308 0.82 LMNA (0.54) LMNATSHRCYP1A2MAPT
Isopropyl Palmitate SCHEMBL28175537 0.81 LMNA (0.85) LMNAGPR84PPARGPPARDPPARA
SCHEMBL28180508 0.80 LMNA (0.56) LMNAAKR1B1GPR84PPARGPPARD
Hydrochloric Acid SCHEMBL11872252 0.80 LMNA (0.52) LMNATSHRCYP1A2MAPT
Hexanoate SCHEMBL7030750 0.79 LMNA (0.81) LMNAAKR1B1GPR84PPARGPPARD
Myristic Acid SCHEMBL10535750 0.77 LMNA (0.85) LMNAAKR1B1GPR84PPARGPPARD
Isopropyl Palmitate SCHEMBL1692109 0.77 LMNA (0.85) LMNAAKR1B1GPR84PPARGPPARD
Isopropyl Palmitate SCHEMBL8566831 0.77 LMNA (0.85) LMNAAKR1B1GPR84PPARGPPARD
Isopropyl Myristate SCHEMBL16399923 0.77 LMNA (0.85) LMNAAKR1B1GPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3034547-B1 A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-10-09 EP claimed
EP-3034545-A1 A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP claimed
EP-3034547-A1 A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP claimed
EP-3577171-B1 AQUEOUS SYSTEM FOR FORMING A COATING ON A SUBSTRATE BASF SE (DE) 2020-11-18 EP disclosed
EP-3034545-B1 A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-11-04 EP disclosed
US-10815383-B2 Pigmented primer composition for forming an n-acyl urea coating BASF SE (DE) 2020-10-27 US disclosed
EP-3233974-B1 A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-02-19 EP disclosed
EP-3328945-B1 PIGMENTED PRIMER COMPOSITION FOR FORMING AN N-ACYL UREA COATING BASF SE (DE) 2019-10-30 EP disclosed
US-10457767-B2 Method of preparing a polycarbodiimide polymer and polycarbodiimide polymer prepared thereby BASF SE (DE) 2019-10-29 US disclosed
EP-3034546-B1 A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-10-16 EP disclosed
EP-3034544-B1 A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-10-16 EP disclosed
US-6489503-B1 COMPOSITION COMPRISING METHYLENE BIS(PHENYLISOCYANATE) COMPONENT AND POSITIVE AMOUNT OF URETONIMINE, WHICH IS STORAGE STABLE AS LIQUID AT TEMPERATURE OF AT LEAST 30 DEGREES C. BASF CORPORATION 2002-12-03 US disclosed
US-6120699-A CONVERTING A PORTION OF THE 4,4'-MDI INTO A POSITIVE AMOUNT OF A CARBODIIMIDE, THE CARBODIIMIDE SUBSEQUENTLY BEING CONVERTED INTO A POSITIVE AMOUNT OF A URETONIMINE IN THE PRESENCE OF EXCESS 4,4'-MDI BASF CORPORATION (US) 2000-09-19 US disclosed
EP-0989116-A1 Storage stable methylene bis(phenylisocyanate) compositions Basf Corporation (US) 2000-03-29 EP disclosed
EP-0308710-A1 Liquid carbodiimide-uretonimine-modified polyphenylene polyisocyanates and polyurethane foams made therefrom BASF Corporation (US) 1989-03-29 EP disclosed
US-4743626-A Liquid carbodiimide-uretonimine modified polymethylene polyphenylene polyisocyanates and polyurethane foams made therefrom BASF CORPORATION (US) 1988-05-10 US disclosed
US-4424288-A Carbodiimide-modified polymethylene polyphenylene polyisocyanates for use in the preparation of polyisocyanurate-polyurethane foams BASF WYANDOTTE CORPORATION (US) 1984-01-03 US disclosed
US-4284730-A Liquid carbodiimide- and uretonimine-isocyanurate-containing polyisocyanate compositions and microcellular foams made therefrom BASF WYANDOTTE CORPORATION (US) 1981-08-18 US disclosed
US-4228095-A Process for the preparation of liquid carbodiimide-modified organic polyisocyanates employing organotin catalysts BASF WYANDOTTE CORPORATION (US) 1980-10-14 US disclosed
US-4018708-A TRANSESTERIFICATION CATALYSTS BASF WYANDOTTE CORPORATION (US) 1977-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10457767-B2 Method of preparing a polycarbodiimide polymer and polycarbodiimide polymer prepared thereby PAICS, PBRM1, PARG LMNA 2029/4885AKR1B1 4210/4885GPR84 4825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.