Butane

Butane

SCHEMBL2855880

CC(C)OC(=O)CCC(=O)O.CCCC

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
FFAR3 O14843 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
EGLN1 Q9GZT9 2/20 0.43
KDM6B O15054 1/20 0.43
KDM5C P41229 1/20 0.43
PHF8 Q9UPP1 1/20 0.43
KDM2A Q9Y2K7 1/20 0.43
TSHR P16473 5/20 0.41
MAPT P10636 1/20 0.40
AKR1B1 P15121 1/20 0.39
ALKBH5 Q6P6C2 1/20 0.39
SUCNR1 Q9BXA5 1/20 0.39
GPR84 Q9NQS5 7/20 0.38
PPARG P37231 6/20 0.38
PPARD Q03181 6/20 0.38
PPARA Q07869 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL191308 0.93 LMNA (0.54) LMNAFFAR3HDAC3HDAC1HDAC2
Hydrochloric Acid SCHEMBL11872252 0.91 LMNA (0.52) LMNAFFAR3HDAC3HDAC1HDAC2
Butane SCHEMBL20558824 0.91 LMNA (0.68) LMNATSHRMAPTALDH1A1
Cyclohexane SCHEMBL27646640 0.87 LMNA (0.48) LMNAEGLN1KDM6BKDM5CPHF8
Butyric Acid SCHEMBL28683379 0.87 LMNA (0.59) LMNAFFAR3HDAC3HDAC1HDAC2
Isopropyl Palmitate SCHEMBL28175537 0.84 LMNA (0.85) LMNATSHRMAPTGPR84PPARG
SCHEMBL28180508 0.84 LMNA (0.56) LMNATSHRMAPTAKR1B1GPR84
SCHEMBL2808264 0.84 LMNA (0.56) LMNATSHRMAPTAKR1B1GPR84
SCHEMBL72471 0.83 LMNA (0.62) LMNATSHRMAPTALDH1A1
Butane SCHEMBL2861696 0.83 LMNA (0.41) LMNAFFAR3HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP claimed
US-11840508-B2 Catalyst system for olefin polymerization and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-12-12 US disclosed
CN-116997578-A Prepolymerized catalyst component for olefin polymerization 巴塞尔聚烯烃意大利有限公司 2023-11-03 CN disclosed
CN-116199995-A High-fluidity polypropylene resin composition and molded article made from the same 韩华道达尔能源有限公司 2023-06-02 CN disclosed
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP disclosed
WO-2023017805-A1 POLYPROPYLENE COMPOSITION AND INJECTION-MOLDED ARTICLE サンアロマー株式会社 2023-02-16 WO disclosed
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
WO-2021015191-A1 EXPANDABLE POLYPROPYLENE COMPOSITION AND INJECTION MOLDED FOAM サンアロマー株式会社 2021-01-28 WO disclosed
US-20200071430-A1 SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2020-03-05 US disclosed
CN-110036068-A Concentrate composition 巴塞尔聚烯烃意大利有限公司 2019-07-19 CN disclosed
CN-104109212-B Solid catalyst component for olefine polymerization and catalyst 北京利和知信科技有限公司 2017-11-07 CN disclosed
CN-104479055-B A kind of dialkoxy-magnesium support type ingredient of solid catalyst and catalyst 任丘市利和科技发展有限公司 2017-06-06 CN disclosed
CN-103476806-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限责任公司 2016-12-07 CN disclosed
US-8822366-B2 Solid titanium catalyst component, catalyst for olefin polymerization and process for polymerizing olefin MITSUI CHEMICALS, INC. (JP) 2014-09-02 US disclosed
EP-2697271-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2014-02-19 EP disclosed
EP-2206731-B1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD MITSUI CHEMICALS INC (JP) 2013-08-28 EP disclosed
WO-2012139897-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2012-10-18 WO disclosed
US-20100227991-A1 SOLID TITANIUM CATALYST COMPONENT, CATALIST FOR OLEFIN POLYMERIZATION AND PROCESS FOR POLYMERIZING OLEFIN MITSUI CHEMICALS, INC. (JP) 2010-09-09 US disclosed
CN-101808800-A Propylene based polymers for injection stretch blow molding FINA TECHNOLOGY 2010-08-18 CN disclosed
EP-2206731-A1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD Mitsui Chemicals, Inc. (JP) 2010-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11840508-B2 Catalyst system for olefin polymerization and use thereof SQSTM1, SAMM50, HPD LMNA 4686/4885FFAR3 4183/4885HDAC3 3051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.