Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853577 | 0.80 | KMT2A (0.56) | KMT2AALDH1A1MEN1MAPTHTT | |
| SCHEMBL544327 | 0.79 | MEN1 (0.59) | KMT2AMEN1MAPTMRGPRX4 | |
| SCHEMBL9930228 | 0.78 | KMT2A (0.56) | KMT2AALDH1A1MEN1MAPTHTT | |
| SCHEMBL6321927 | 0.76 | ALOX5 (0.62) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL11454145 | 0.75 | KMT2A (0.63) | KMT2AALDH1A1MEN1MAPTHTT | |
| SCHEMBL8064713 | 0.73 | NPC1 (0.62) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL5447871 | 0.73 | ALDH1A1 (1.00) | KMT2AALDH1A1MEN1MAPTHTT | |
| SCHEMBL30152252 | 0.72 | KMT2A (0.47) | KMT2AALDH1A1MEN1MAPTHTT | |
| SCHEMBL31075460 | 0.72 | HTT (0.60) | KMT2AALDH1A1MEN1MAPTHTT | |
| SCHEMBL447240 | 0.72 | HTT (0.60) | KMT2AALDH1A1MEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083612-A | A kind of fluorine-containing Triamine monomer and its preparation method and application | 湖北大学 | 2016-11-09 | — | — | CN | claimed |
| CN-106083612-A | A kind of fluorine-containing Triamine monomer and its preparation method and application | 湖北大学 | 2016-11-09 | — | — | CN | disclosed |