Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591794 | 0.86 | TSHR (0.48) | THRBTSHRALDH1A1TDP1 | |
| SCHEMBL9421578 | 0.84 | THRB (0.37) | THRBTSHRHSD17B10ALDH1A1TDP1 | |
| SCHEMBL4063408 | 0.84 | TDP1 (0.50) | THRBTSHRHSD17B10ALDH1A1TDP1 | |
| SCHEMBL9421555 | 0.81 | THRB (0.38) | THRBTSHRHTT | |
| SCHEMBL9421559 | 0.81 | THRB (0.38) | THRBTSHRHTT | |
| SCHEMBL9421569 | 0.81 | TSHR (0.38) | THRBTSHRALDH1A1 | |
| SCHEMBL11210683 | 0.81 | TSHR (0.42) | THRBTSHRHSD17B10USP2 | |
| SCHEMBL11252889 | 0.80 | TDP1 (0.54) | THRBTSHRHSD17B10ALDH1A1TDP1 | |
| SCHEMBL4067172 | 0.80 | THRB (0.39) | THRBTSHRHSD17B10ALDH1A1TDP1 | |
| SCHEMBL4815158 | 0.80 | TDP1 (0.54) | THRBTSHRHSD17B10ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104004196-B | A kind of preparation method and applications of degradable over-branched polyamidoamine | 健雄职业技术学院 | 2016-08-31 | — | — | CN | claimed |
| CN-104004196-B | A kind of preparation method and applications of degradable over-branched polyamidoamine | 健雄职业技术学院 | 2016-08-31 | — | — | CN | disclosed |