Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4062183 | 0.91 | TSHR (0.42) | THRBTSHRALDH1A1PLA2G2C | |
| SCHEMBL4065864 | 0.87 | THRB (0.44) | THRBTSHRALDH1A1 | |
| SCHEMBL4064266 | 0.83 | ALDH1A1 (0.45) | THRBTSHRALDH1A1 | |
| SCHEMBL28083231 | 0.80 | THRB (0.43) | THRBTSHRHSD17B10TDP1ALDH1A1 | |
| SCHEMBL4063408 | 0.78 | TDP1 (0.50) | THRBTSHRHSD17B10TDP1ALDH1A1 | |
| SCHEMBL2515977 | 0.75 | TSHR (0.39) | THRBTSHRALDH1A1 | |
| SCHEMBL11210683 | 0.75 | TSHR (0.42) | THRBTSHRHSD17B10 | |
| SCHEMBL11240653 | 0.74 | TDP1 (0.54) | THRBTSHRHSD17B10TDP1ALDH1A1 | |
| SCHEMBL4815158 | 0.74 | TDP1 (0.54) | THRBTSHRHSD17B10TDP1ALDH1A1 | |
| SCHEMBL11252889 | 0.74 | TDP1 (0.54) | THRBTSHRHSD17B10TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158302-A2 | VISCOUS ALPHA-CYANOACRYLATE COMPOSITIONS | CLOSURE MEDICAL CORPORATION (US) | 2009-12-30 | — | — | WO | disclosed |