Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22939 | 0.95 | CASP1 (0.56) | CASP1ADRB2ADRB1ALDH1A1CYP2D6 | |
| SCHEMBL29572218 | 0.95 | CASP1 (0.56) | CASP1ADRB2ADRB1ALDH1A1CYP2D6 | |
| SCHEMBL253615 | 0.95 | CASP1 (0.56) | CASP1ADRB2ADRB1ALDH1A1CYP2D6 | |
| SCHEMBL3685278 | 0.95 | CASP1 (0.56) | CASP1ADRB2ADRB1ALDH1A1CYP2D6 | |
| SCHEMBL31506886 | 0.95 | CASP1 (0.56) | CASP1ADRB2ADRB1ALDH1A1CYP2D6 | |
| SCHEMBL29572016 | 0.95 | CASP1 (0.56) | CASP1ADRB2ADRB1ALDH1A1CYP2D6 | |
| SCHEMBL30536648 | 0.83 | CASP1 (0.52) | CASP1ADRB2ADRB1CYP2D6NFKB1 | |
| SCHEMBL26690540 | 0.82 | CASP1 (0.41) | CASP1KMT2A | |
| SCHEMBL9890698 | 0.82 | CASP1 (0.44) | CASP1ALDH1A1NPC1HTTTHRB | |
| SCHEMBL4632799 | 0.81 | CASP1 (0.70) | CASP1ADRB2ADRB1ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104136415-B | Phenyl carbamate compounds for use in preventing or treating stroke | 比皮艾思药物研发有限公司 | 2016-09-07 | — | — | CN | disclosed |