SCHEMBL29572016

SCHEMBL29572016

COC(=O)C(O)c1ccccc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.56
ADRB2 P07550 2/20 0.45
ADRB1 P08588 2/20 0.45
ALDH1A1 P00352 3/20 0.44
KMT2A Q03164 1/20 0.44
THRB P10828 1/20 0.44
NR1I2 O75469 1/20 0.44
ABCB11 O95342 1/20 0.44
CHRM2 P08172 1/20 0.44
ADRA2A P08913 1/20 0.44
CYP2B6 P20813 1/20 0.44
DRD1 P21728 1/20 0.44
HTR2A P28223 1/20 0.44
SLC6A4 P31645 1/20 0.44
CYP2C19 P33261 1/20 0.44
OPRM1 P35372 1/20 0.44
OPRK1 P41145 1/20 0.44
HTR2B P41595 1/20 0.44
KCNH2 Q12809 1/20 0.44
P2RY12 Q9H244 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3685278 1.00 CASP1 (0.56) CASP1ADRB2ADRB1ALDH1A1KMT2A
SCHEMBL29572218 1.00 CASP1 (0.56) CASP1ADRB2ADRB1ALDH1A1KMT2A
SCHEMBL253615 1.00 CASP1 (0.56) CASP1ADRB2ADRB1ALDH1A1KMT2A
SCHEMBL22939 1.00 CASP1 (0.56) CASP1ADRB2ADRB1ALDH1A1KMT2A
SCHEMBL31506886 1.00 CASP1 (0.56) CASP1ADRB2ADRB1ALDH1A1KMT2A
Methylene Chloride SCHEMBL28084097 0.95 CASP1 (0.56) CASP1ADRB2ADRB1ALDH1A1KMT2A
SCHEMBL30536648 0.88 CASP1 (0.52) CASP1ADRB2ADRB1THRBNR1I2
SCHEMBL9890698 0.86 CASP1 (0.44) CASP1ALDH1A1KMT2ATHRBNR1I2
SCHEMBL27962041 0.86 CYP1A2 (0.46) CASP1ALDH1A1KMT2ACYP2D6NFKB1
SCHEMBL6487230 0.83 ALDH1A1 (0.56) CASP1ADRB2ADRB1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119913129-A Carboxylesterase mutant and application thereof in preparation of (R) -o-chloromandelic acid 湖州师范学院 2025-05-02 CN claimed
CN-116655652-A New synthesis method of clopidogrel 宿迁盛基医药科技有限公司 2023-08-29 CN claimed
CN-119913129-A Carboxylesterase mutant and application thereof in preparation of (R) -o-chloromandelic acid 湖州师范学院 2025-05-02 CN disclosed
CN-116655652-A New synthesis method of clopidogrel 宿迁盛基医药科技有限公司 2023-08-29 CN disclosed
CN-116655652-A New synthesis method of clopidogrel 宿迁盛基医药科技有限公司 2023-08-29 CN disclosed
CN-116023262-A Preparation method of clopidogrel bisulfate and intermediate thereof 浙江乐普药业股份有限公司 2023-04-28 CN disclosed
CN-116023262-A Preparation method of clopidogrel bisulfate and intermediate thereof 浙江乐普药业股份有限公司 2023-04-28 CN disclosed
CN-109867684-B Preparation method of II-type clopidogrel hydrogen sulfate 武汉武药制药有限公司 2022-06-17 CN disclosed
CN-109867685-B Preparation method of clopidogrel hydrogen sulfate II type 武汉武药制药有限公司 2022-04-08 CN disclosed