SCHEMBL28084348

SCHEMBL28084348

COC(=O)C1(CCl)CCCC1=O

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.38
CYP2C19 P33261 6/20 0.36
CYP3A4 P08684 2/20 0.34
TSHR P16473 2/20 0.34
MAPT P10636 3/20 0.33
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
TACR1 P25103 1/20 0.32
TACR3 P29371 1/20 0.32
MEN1 O00255 1/20 0.31
CYP2D6 P10635 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2648433 0.86 CYP2C19 (0.36) NPSR1CYP2C19CYP3A4TSHRMAPT
SCHEMBL1417675 0.84 CYP4F2 (0.37) NPSR1CYP2C19CYP3A4TSHRMAPT
SCHEMBL4811675 0.84 MAPT (0.41) NPSR1CYP2C19CYP3A4TSHRMAPT
SCHEMBL31369191 0.84 CYP4F2 (0.36) NPSR1CYP2C19CYP3A4TSHRMAPT
SCHEMBL7626939 0.81 CYP2C19 (0.36) NPSR1CYP2C19CYP3A4TSHRMAPT
SCHEMBL22211342 0.79 TACR1 (0.44) CYP2C19CYP3A4TSHRMAPTKDM4E
SCHEMBL9079831 0.79 CYP2C19 (0.34) NPSR1CYP2C19CYP3A4TSHRMAPT
SCHEMBL8468255 0.79 CYP2C19 (0.34) NPSR1CYP2C19CYP3A4TSHRMAPT
SCHEMBL9732373 0.79 CYP2C19 (0.34) NPSR1CYP2C19CYP3A4TSHRMAPT
SCHEMBL10970901 0.78 RAD52 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103596917-B The manufacture method of cyclopentanone compound and midbody compound 株式会社吴羽 2016-08-17 CN disclosed