Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811675 | 0.86 | MAPT (0.41) | CYP4F2CYP4A11CYP2C19CYP3A4NPSR1 | |
| SCHEMBL2648433 | 0.84 | CYP2C19 (0.36) | CYP4F2CYP4A11CYP2C19CYP3A4NPSR1 | |
| SCHEMBL28084348 | 0.84 | NPSR1 (0.38) | CYP4F2CYP4A11CYP2C19CYP3A4NPSR1 | |
| SCHEMBL7626939 | 0.83 | CYP2C19 (0.36) | CYP4F2CYP4A11CYP2C19CYP3A4NPSR1 | |
| SCHEMBL9079831 | 0.80 | CYP2C19 (0.34) | CYP4F2CYP4A11CYP2C19CYP3A4NPSR1 | |
| SCHEMBL8468255 | 0.80 | CYP2C19 (0.34) | CYP4F2CYP4A11CYP2C19CYP3A4NPSR1 | |
| SCHEMBL9732373 | 0.80 | CYP2C19 (0.34) | CYP4F2CYP4A11CYP2C19CYP3A4NPSR1 | |
| SCHEMBL31369191 | 0.79 | CYP4F2 (0.36) | CYP4F2CYP4A11CYP2C19CYP3A4NPSR1 | |
| SCHEMBL14799327 | 0.79 | CYP2C19 (0.33) | CYP4F2CYP4A11CYP2C19CYP3A4NPSR1 | |
| SCHEMBL29168788 | 0.79 | SIRT2 (0.40) | CYP4F2CYP4A11CYP2C19CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298783-B1 | Anti-viral nucleoside analogs and methods for treating viral infections, especially hiv infections | UNIV YALE (US) | 2017-12-06 | — | — | EP | disclosed |
| CN-103596917-B | The manufacture method of cyclopentanone compound and midbody compound | 株式会社吴羽 | 2016-08-17 | — | — | CN | disclosed |
| US-9126971-B2 | Anti-viral nucleoside analogs and methods for treating viral infections, especially HIV infections | YALE UNIVERSITY (US) | 2015-09-08 | — | — | US | disclosed |
| CN-104540818-A | Method for producing cycloalkanol derivative, and method for producing azole derivative | KUREHA CORP | 2015-04-22 | — | — | CN | disclosed |
| US-20120252751-A1 | ANTI-VIRAL NUCLEOSIDE ANALOGS AND METHODS FOR TREATING VIRAL INFECTIONS, ESPECIALLY HIV INFECTIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-10-04 | — | — | US | disclosed |
| US-8193165-B2 | Anti-viral nucleoside analogs and methods for treating viral infections, especially HIV infections | YALE UNIVERSITY (US) | 2012-06-05 | — | — | US | disclosed |
| CN-102174038-A | Anti-viral nucleoside for treating viral infections | UNIV YALE | 2011-09-07 | — | — | CN | disclosed |
| CN-1777432-B | Antiviral nucleoside analogs for HIV infection | UNIV YALE | 2011-06-08 | — | — | CN | disclosed |
| EP-2298783-A1 | Anti-viral nucleoside analogs and methods for treating viral infections, especially hiv infections | Yale University (US) | 2011-03-23 | — | — | EP | disclosed |
| US-20100048500-A1 | Anti-viral nucleoside analogs and methods for treating viral infections, especially HIV infections | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-02-25 | — | — | US | disclosed |
| US-7589078-B2 | Using a dideoxy and didehydro nucleoside | YALE UNIVERSITY (US) | 2009-09-15 | — | — | US | disclosed |
| EP-1653976-A4 | ANTI-VIRAL NUCLEOSIDE ANALOGS AND METHODS FOR TREATING VIRAL INFECTIONS, ESPECIALLY HIV INFECTIONS | UNIV YALE (US) | 2009-07-29 | — | — | EP | disclosed |
| CN-1777432-A | Antiviral nucleoside analogs and methods for treating viral infections, particularly HIV infections | UNIV YALE (US) | 2006-05-24 | — | — | CN | disclosed |
| EP-1653976-A1 | ANTI-VIRAL NUCLEOSIDE ANALOGS AND METHODS FOR TREATING VIRAL INFECTIONS, ESPECIALLY HIV INFECTIONS | YALE UNIVERSITY (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005011709-A1 | ANTI-VIRAL NUCLEOSIDE ANALOGS AND METHODS FOR TREATING VIRAL INFECTIONS, ESPECIALLY HIV INFECTIONS | YALE UNIVERSITY (US) | 2005-02-10 | — | — | WO | disclosed |
| US-20040167096-A1 | Anti-viral nucleoside analogs and methods for treating viral infections, especially HIV infections | YALE UNIVERSITY | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048500-A1 | Anti-viral nucleoside analogs and methods for treating viral infections, especially HIV infections | TYMP, ITPA, SAMHD1 | CYP4F2 3304/4885CYP4A11 2599/4885CYP2C19 1532/4885 |
| US-20120252751-A1 | ANTI-VIRAL NUCLEOSIDE ANALOGS AND METHODS FOR TREATING VIRAL INFECTIONS, ESPECIALLY HIV INFECTIONS | TYMP, ITPA, SAMHD1 | CYP4F2 3304/4885CYP4A11 2599/4885CYP2C19 1532/4885 |
| US-20040167096-A1 | Anti-viral nucleoside analogs and methods for treating viral infections, especially HIV infections | CCR1, CCR4, CCR3 | CYP4F2 1191/4885CYP4A11 340/4885CYP2C19 3548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.