Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 20/20 | 0.55 |
| ▸ | PRKAB2 | O43741 | 8/20 | 0.51 |
| ▸ | PRKAG1 | P54619 | 8/20 | 0.51 |
| ▸ | PRKAA1 | Q13131 | 8/20 | 0.51 |
| ▸ | PRKAG3 | Q9UGI9 | 8/20 | 0.51 |
| ▸ | PRKAG2 | Q9UGJ0 | 8/20 | 0.51 |
| ▸ | PRKAB1 | Q9Y478 | 8/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956150 | 0.78 | PRKAA2 (0.52) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| Formamide SCHEMBL15154724 | 0.76 | PRKAA2 (0.46) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| SCHEMBL518546 | 0.76 | HRH3 (0.61) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| SCHEMBL16190086 | 0.75 | PRKAA2 (0.74) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| SCHEMBL18296234 | 0.75 | KMT2A (0.60) | — | |
| SCHEMBL518540 | 0.74 | PRKAA2 (0.81) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| SCHEMBL7238995 | 0.74 | HRH3 (0.65) | — | |
| SCHEMBL10284623 | 0.73 | PRKAA2 (0.68) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| SCHEMBL518389 | 0.73 | PRKAA2 (0.74) | PRKAA2PRKAB2PRKAG1PRKAA1PRKAG3 | |
| Hydrochloric Acid SCHEMBL10625447 | 0.73 | HRH3 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103201267-B | AMPK-activating heterocyclic compounds and methods of use thereof | 里格尔药品股份有限公司 | 2016-08-17 | — | — | CN | disclosed |