Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10625447 | 0.99 | HRH3 (0.64) | HRH3MEN1KMT2ATHRBDRD2 | |
| SCHEMBL8844253 | 0.93 | HRH3 (0.60) | HRH3MEN1KMT2ATHRBDRD2 | |
| SCHEMBL27353627 | 0.86 | SIGMAR1 (0.61) | MEN1KMT2ADRD2ACHECCR5 | |
| SCHEMBL1002852 | 0.84 | MEN1 (0.81) | MEN1KMT2ADRD2ACHECCR5 | |
| SCHEMBL7887513 | 0.84 | HRH3 (0.57) | HRH3THRBACHECHRM4CCR3 | |
| SCHEMBL7571134 | 0.81 | MEN1 (0.88) | MEN1KMT2ADRD2ACHECCR5 | |
| SCHEMBL9070278 | 0.81 | MEN1 (0.67) | MEN1KMT2ADRD2ACHECCR5 | |
| SCHEMBL4576884 | 0.81 | CCR3 (0.74) | HRH3MEN1KMT2ATHRBCHRM4 | |
| SCHEMBL8659907 | 0.80 | MEN1 (0.65) | MEN1KMT2ADRD2ACHECCR5 | |
| SCHEMBL2588250 | 0.80 | MEN1 (0.65) | MEN1KMT2ADRD2ACHECCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664273-B2 | Having at least cyanobenzyl and amidobenzyl substituents; obesity, metabolic disorders, eating disorders such as hyperphagia and diabetes | SCHERING CORPORATION | 2003-12-16 | — | — | US | disclosed |
| EP-0609282-A1 | CYCLOHEXANEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-08-10 | — | — | EP | disclosed |
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |
| WO-1993008181-A1 | CYCLOHEXANEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-04-29 | — | — | WO | disclosed |
| EP-0537980-A1 | Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |