Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21620292 | 0.74 | NPC1 (0.52) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL2936256 | 0.74 | SMN1; SMN2 (0.78) | LMNAGAASMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL16049296 | 0.73 | ALDH1A1 (0.45) | GAAMAPT | |
| SCHEMBL21652228 | 0.73 | TRPV1 (0.64) | LMNASMN1; SMN2KCNK9MAPTTP53 | |
| SCHEMBL10800489 | 0.72 | TDP1 (0.73) | LMNAGAASMN1; SMN2 | |
| SCHEMBL21652233 | 0.72 | HDAC8 (0.51) | LMNAGAASMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL3776667 | 0.71 | KCNK3 (0.65) | LMNAKCNK3KCNK9PTGS1PTPRC | |
| SCHEMBL1499598 | 0.70 | SMN1; SMN2 (0.68) | SMN1; SMN2F2RMAPTABL1MEN1 | |
| SCHEMBL11204897 | 0.70 | NPC1 (0.70) | GAASMN1; SMN2KCNK3KCNK9PTGS1 | |
| SCHEMBL28070419 | 0.70 | GAA (0.46) | GAASMN1; SMN2MAPTTP53ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837491-B | A kind of novel carboxamide derivative fungicide and its preparation method and application | 山东省联合农药工业有限公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-105837491-A | Novel carboxamide derivative bactericide, preparation method and application thereof | 山东省联合农药工业有限公司 | 2016-08-10 | — | — | CN | disclosed |