Phenol

Phenol

SCHEMBL28085368

CCCCCCCc1ccccc1C(C)Cc1ccccc1.Oc1ccccc1

nearest known ligand 0.49

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 8/20 0.49
CYSLTR1 Q9Y271 8/20 0.49
LIPG Q9Y5X9 1/20 0.44
ESR1 P03372 2/20 0.44
ADRA2A P08913 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
TACR2 P21452 2/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
SHBG P04278 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
HSPD1 P10809 1/20 0.44
ADRB3 P13945 1/20 0.44
HTR2C P28335 1/20 0.44
HSPE1 P61604 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1955875 0.82 CYSLTR2 (0.49) CYSLTR2CYSLTR1LIPGTP53CYP3A4
SCHEMBL1955190 0.82 CYSLTR2 (0.49) CYSLTR2CYSLTR1LIPGTP53CYP3A4
SCHEMBL1954271 0.82 CYSLTR2 (0.49) CYSLTR2CYSLTR1LIPGTP53CYP3A4
SCHEMBL1955655 0.82 CYSLTR2 (0.49) CYSLTR2CYSLTR1LIPGTP53CYP3A4
SCHEMBL1952594 0.82 CYSLTR2 (0.49) CYSLTR2CYSLTR1LIPGTP53CYP3A4
SCHEMBL6546357 0.81 SIGMAR1 (0.50) SLC6A2SLC6A4SLC6A3LMNAADORA2A
SCHEMBL1952709 0.80 CYSLTR2 (0.47) CYSLTR2CYSLTR1LIPGPPARABID
Phenol SCHEMBL27403989 0.79 LIPG (0.61) CYSLTR2CYSLTR1LIPGESR1ADRA2A
Phenol SCHEMBL28178409 0.79 LIPG (0.61) CYSLTR2CYSLTR1LIPGESR1ADRA2A
Phenol SCHEMBL28177861 0.79 POLB (0.43) ESR1SLC6A2SLC6A4SLC6A3ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103553972-B Method for the preparation of n-substituted carbamic acid ester and method for the preparation of isocyanate using the n-substituted carbamic acid ester 旭化成株式会社 2017-04-12 CN disclosed
CN-103588680-B N-substituted carbamate conveying with and storage compositions and manufacture isocyanates method 旭化成株式会社 2016-08-10 CN disclosed