Monothioglycerol

Monothioglycerol

SCHEMBL28085371

O=C(O)CS.OCC(O)CS

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.68
ALDH1A1 P00352 2/20 0.40
SLC22A6 Q4U2R8 1/20 0.39
OR51E2 Q9H255 1/20 0.38
PTGS1 P23219 1/20 0.35
SLC7A11 Q9UPY5 1/20 0.35
ENPEP Q07075 6/20 0.34
ANPEP P15144 3/20 0.34
FOLH1 Q04609 1/20 0.34
GABRR1 P24046 2/20 0.33
NR1I2 O75469 1/20 0.33
CYP1A2 P05177 1/20 0.33
HTT P42858 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
THRB P10828 1/20 0.33
GSTK1 Q9Y2Q3 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Monothioglycerol SCHEMBL331613 1.00 LMNA (0.68) LMNAALDH1A1SLC22A6OR51E2PTGS1
Monothioglycerol SCHEMBL11610632 0.97 LMNA (0.65) LMNAALDH1A1SLC22A6OR51E2PTGS1
Thioglycolic Acid SCHEMBL27401446 0.90 LMNA (0.52) LMNAALDH1A1SLC22A6OR51E2ENPEP
Glycerin SCHEMBL97662 0.89 LMNA (0.53) LMNAALDH1A1SLC22A6OR51E2PTGS1
Glycerin SCHEMBL560044 0.89 LMNA (0.53) LMNAALDH1A1SLC22A6OR51E2PTGS1
Glycerin SCHEMBL97353 0.89 LMNA (0.53) LMNAALDH1A1SLC22A6OR51E2PTGS1
Glycerin SCHEMBL332069 0.89 LMNA (0.53) LMNAALDH1A1SLC22A6OR51E2PTGS1
Glycerin SCHEMBL10783902 0.89 LMNA (0.53) LMNAALDH1A1SLC22A6OR51E2PTGS1
Thioglycolic Acid SCHEMBL6243518 0.86 LMNA (0.45) LMNASLC22A6PTGS1SLC7A11ENPEP
Monothioglycerol SCHEMBL7786564 0.84 LMNA (0.68) LMNAALDH1A1SLC22A6OR51E2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105899563-B Composition and optical article containing polyurethaneurea and method of making the same PPG工业俄亥俄公司 2019-06-11 CN disclosed
CN-108690180-A Composition and optical goods containing polyurethane-urea and preparation method thereof PPG工业俄亥俄公司 2018-10-23 CN disclosed
CN-107922578-A It is used to prepare the composition of molded polymer article PPG工业俄亥俄公司 2018-04-17 CN disclosed
CN-105899563-A Composition and optical article containing polyurethaneurea and method of making the same PPG工业俄亥俄公司 2016-08-24 CN disclosed