Monothioglycerol

Monothioglycerol

SCHEMBL331613

O=C(O)CS.O=C(O)CS.OCC(O)CS

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.68
ALDH1A1 P00352 2/20 0.40
SLC22A6 Q4U2R8 1/20 0.39
OR51E2 Q9H255 1/20 0.38
PTGS1 P23219 1/20 0.35
SLC7A11 Q9UPY5 1/20 0.35
ENPEP Q07075 6/20 0.34
ANPEP P15144 3/20 0.34
FOLH1 Q04609 1/20 0.34
GABRR1 P24046 2/20 0.33
NR1I2 O75469 1/20 0.33
CYP1A2 P05177 1/20 0.33
HTT P42858 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
THRB P10828 1/20 0.33
GSTK1 Q9Y2Q3 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Monothioglycerol SCHEMBL28085371 1.00 LMNA (0.68) LMNAALDH1A1SLC22A6OR51E2PTGS1
Monothioglycerol SCHEMBL11610632 0.97 LMNA (0.65) LMNAALDH1A1SLC22A6OR51E2PTGS1
Thioglycolic Acid SCHEMBL27401446 0.90 LMNA (0.52) LMNAALDH1A1SLC22A6OR51E2ENPEP
Glycerin SCHEMBL97662 0.89 LMNA (0.53) LMNAALDH1A1SLC22A6OR51E2PTGS1
Glycerin SCHEMBL560044 0.89 LMNA (0.53) LMNAALDH1A1SLC22A6OR51E2PTGS1
Glycerin SCHEMBL97353 0.89 LMNA (0.53) LMNAALDH1A1SLC22A6OR51E2PTGS1
Glycerin SCHEMBL332069 0.89 LMNA (0.53) LMNAALDH1A1SLC22A6OR51E2PTGS1
Glycerin SCHEMBL10783902 0.89 LMNA (0.53) LMNAALDH1A1SLC22A6OR51E2PTGS1
Thioglycolic Acid SCHEMBL6243518 0.86 LMNA (0.45) LMNASLC22A6PTGS1SLC7A11ENPEP
Monothioglycerol SCHEMBL7786564 0.84 LMNA (0.68) LMNAALDH1A1SLC22A6OR51E2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2921511-B1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL AND MANUFACTURING METHOD FOR SAME MITSUI CHEMICALS INC (JP) 2017-11-01 EP claimed
US-9778397-B2 Polymerizable composition, optical material, and manufacturing method of the same MITSUI CHEMICALS, INC. (JP) 2017-10-03 US claimed
US-20150331147-A1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL, AND MANUFACTURING METHOD OF THE SAME MITSUI CHEMICALS, INC. (JP) 2015-11-19 US claimed
US-6342571-B1 POLYMERIZABLE MIXTURE OF THIO(METH)ACRYLATE, VINYL AROMATIC, POLYTHIOL, AND UNSATURATED ANHYDRIDE COMONOMERS PPG INDUSTRIES OHIO, INC. 2002-01-29 US claimed
US-12625430-B2 Colored photosensitive resin composition and mutilayer cured film prepared therefrom DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2026-05-12 US disclosed
US-20260085147-A1 SOLVENT-BORNE COATING COMPOSITIONS COMPRISING A WATER-DISPERSIBLE POLYISOCYANATE PPG INDUSTRIES OHIO, INC. (US) 2026-03-26 US disclosed
US-20250382514-A1 CURABLE ADHESIVE COMPOSITION COMPRISING MALEIMIDE AND THIOL HENKEL AG & CO KGAA (DE) 2025-12-18 US disclosed
EP-4587499-A1 SOLVENT-BORNE COATING COMPOSITIONS COMPRISING A WATER-DISPERSIBLE POLYISOCYANATE PPG Industries Ohio Inc. (US) 2025-07-23 EP disclosed
EP-3841141-B1 A COMPOSITION, PREPARATION METHOD AND APPLICATION THEREOF COVESTRO DEUTSCHLAND AG (DE) 2025-01-01 EP disclosed
EP-3325532-B1 COMPOSITION FOR PREPARING MOLDED POLYMERIC ARTICLE PPG IND OHIO INC (US) 2024-09-04 EP disclosed
US-11965108-B2 Composition, preparation method and application thereof COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-04-23 US disclosed
WO-2024059451-A1 SOLVENT-BORNE COATING COMPOSITIONS COMPRISING A WATER-DISPERSIBLE POLYISOCYANATE PPG INDUSTRIES OHIO, INC. (US) 2024-03-21 WO disclosed
EP-1177241-A1 OPTICAL RESIN COMPOSITION COMPRISING THIOL-ENE PREPOLYMER PPG Industries Ohio, Inc. (US) 2002-02-06 EP disclosed
US-6342571-B1 POLYMERIZABLE MIXTURE OF THIO(METH)ACRYLATE, VINYL AROMATIC, POLYTHIOL, AND UNSATURATED ANHYDRIDE COMONOMERS PPG INDUSTRIES OHIO, INC. 2002-01-29 US disclosed
US-20020010313-A1 Polyfunctional thiirane compounds PPG INDUSTRIES OHIO, INC. 2002-01-24 US disclosed
US-20010047043-A1 Method of preparing a polymerizate PPG INDUSTRIES OHIO, INC. 2001-11-29 US disclosed
WO-2000064964-A1 OPTICAL RESIN COMPOSITION COMPRISING THIOL-ENE PREPOLYMER PPG INDUSTRIES OHIO, INC. (US) 2000-11-02 WO disclosed
US-5976422-A POLYUNSATURATED MONOMER, BIS(MERCAPTOHYDROCARBONOIC ACID ESTER) OF 1-THIOGLYCEROL, OPTIONALLY UNSATURATED ANHYDRIDE; PHOTOCHROMIC ARTICLE PPG INDUSTRIES OHIO, INC. (US) 1999-11-02 US disclosed
US-5942158-A PHOTOCHROMIC ARTICLE PPG INDUSTRIES OHIO, INC. (US) 1999-08-24 US disclosed
US-5932681-A PHOTOCHROMIC ARTICLE PPG INDUSTRIES OHIO, INC. (US) 1999-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12625430-B2 Colored photosensitive resin composition and mutilayer cured film prepared therefrom RAD51, SMURF1, SMARCA1 LMNA 2616/4885ALDH1A1 1348/4885SLC22A6 4536/4885
US-20260085147-A1 SOLVENT-BORNE COATING COMPOSITIONS COMPRISING A WATER-DISPERSIBLE POLYISOCYANATE PARG, PUF60, SRM LMNA 3233/4885ALDH1A1 2671/4885SLC22A6 1314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.