Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96800 | 0.88 | ALOX5 (0.58) | MAOBALOX5MAPTL3MBTL1GSTP1 | |
| SCHEMBL6987612 | 0.83 | MAOB (0.58) | MAOBALOX5MAPTL3MBTL1LMNA | |
| SCHEMBL7606123 | 0.79 | MAOB (0.50) | MAOBALOX5ABCB1HTR1ADRD2 | |
| SCHEMBL1962771 | 0.79 | MAOB (0.64) | MAOBMAPTTDP1L3MBTL1CYP2C19 | |
| SCHEMBL1963431 | 0.79 | HDAC8 (0.52) | MAOBALOX5MAPTTDP1HDAC8 | |
| SCHEMBL27252705 | 0.78 | MAOB (0.74) | MAOBALOX5 | |
| SCHEMBL6035769 | 0.78 | MAOB (0.51) | MAOBALOX5MAPTMAPK1TDP1 | |
| SCHEMBL4032308 | 0.77 | ELANE (0.49) | MAOBALOX5ABCB1HTR1ADRD2 | |
| SCHEMBL4028358 | 0.77 | ABCB1 (0.47) | MAOBALOX5ABCB1ABCG2HTR1A | |
| SCHEMBL28085579 | 0.77 | APP (0.46) | ABCB1MAPTMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849111-A | Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease | 依如睦生物科技株式会社 | 2016-08-10 | — | — | CN | disclosed |