Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085577 | 0.77 | MAOB (0.46) | CYP1A2ABCB1HTR1ADRD2ABCG2 | |
| SCHEMBL10499877 | 0.76 | MAOB (0.54) | FFAR4 | |
| SCHEMBL791445 | 0.75 | CYP4F2 (0.66) | ABCB1HTR1ADRD2ENPP2BCHE | |
| SCHEMBL21436894 | 0.75 | APP (0.48) | APPCYP2C9KMT2AMEN1FFAR4 | |
| SCHEMBL96800 | 0.74 | ALOX5 (0.58) | CYP1A2CYP3A4MAPTL3MBTL1LMNA | |
| SCHEMBL4407617 | 0.74 | ENPP2 (0.62) | CYP1A2KMT2AMEN1FFAR4MAPT | |
| SCHEMBL3558279 | 0.73 | NPC1 (0.51) | APPKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10252335 | 0.73 | HTR1A (0.69) | ABCB1HTR1ADRD2ABCG2MAPT | |
| SCHEMBL29153609 | 0.73 | MAOB (0.57) | CYP1A2KMT2AMEN1ABCB1HTR1A | |
| SCHEMBL8306114 | 0.72 | KDM4E (0.64) | APPKDM4ECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849111-A | Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease | 依如睦生物科技株式会社 | 2016-08-10 | — | — | CN | disclosed |