Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31729425 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MEN1CYP1A2KMT2AKDM4E | |
| SCHEMBL6571203 | 0.90 | MAPT (0.54) | ALDH1A1MEN1CYP1A2KMT2AKDM4E | |
| SCHEMBL16166721 | 0.89 | KDM4E (0.61) | ALDH1A1MEN1CYP1A2KMT2AKDM4E | |
| SCHEMBL17565226 | 0.86 | MAPT (0.54) | ALDH1A1MEN1CYP1A2KMT2AKDM4E | |
| SCHEMBL9059478 | 0.84 | CTSB (0.56) | ALDH1A1MEN1CYP1A2KMT2AKDM4E | |
| SCHEMBL3435480 | 0.84 | MAPT (0.48) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL16166864 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MEN1CYP1A2KMT2AKDM4E | |
| SCHEMBL28551108 | 0.81 | MAPT (0.48) | ALDH1A1MEN1CYP1A2KMT2AKDM4E | |
| SCHEMBL16054145 | 0.80 | MAPT (0.51) | ALDH1A1MEN1CYP1A2KMT2ALMNA | |
| SCHEMBL325422 | 0.79 | NPC1 (0.70) | ALDH1A1MEN1CYP1A2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103588704-B | INHIBITORS OF FOCAL ADHESION KINASE | 斯克里普斯研究学院 | 2016-09-14 | — | — | CN | disclosed |