Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20959159 | 0.86 | KMT2A (0.47) | RIPK1HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL20959158 | 0.86 | KMT2A (0.47) | RIPK1HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL20959427 | 0.86 | KMT2A (0.47) | RIPK1HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL5968844 | 0.82 | RIPK1 (0.51) | RIPK1ALDH1A1SMN1; SMN2POLBHSP90AA1 | |
| SCHEMBL6310814 | 0.81 | RIPK1 (0.50) | RIPK1ALDH1A1SMN1; SMN2POLBHSP90AA1 | |
| SCHEMBL9294528 | 0.81 | CHRNB2 (0.53) | RIPK1HTTMEN1KMT2ALMNA | |
| SCHEMBL5746647 | 0.81 | RIPK1 (0.50) | RIPK1ALDH1A1SMN1; SMN2POLBHSP90AA1 | |
| SCHEMBL5747606 | 0.81 | RIPK1 (0.50) | RIPK1ALDH1A1SMN1; SMN2POLBHSP90AA1 | |
| SCHEMBL9294538 | 0.81 | CHRNB2 (0.53) | RIPK1HTTMEN1KMT2ALMNA | |
| SCHEMBL5746649 | 0.81 | RIPK1 (0.50) | RIPK1ALDH1A1SMN1; SMN2POLBHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764887-A | Nitrogen-containing saturated heterocyclic compound | 住友化学株式会社 | 2016-07-13 | — | — | CN | disclosed |