Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360755 | 0.88 | THRB (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL27984348 | 0.87 | THRB (0.46) | THRBTSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL8362106 | 0.83 | THRB (0.61) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5109136 | 0.80 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| Ammonia Solution, Strong SCHEMBL8025356 | 0.78 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL30876969 | 0.78 | THRB (0.53) | THRBTSHRCHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL10629539 | 0.77 | THRB (0.50) | THRBTSHRCHRM5CHRM1CHRM3 | |
| Hydrogen Sulfide SCHEMBL28835969 | 0.76 | THRB (0.71) | THRBTSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL10979538 | 0.75 | THRB (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL154342 | 0.75 | THRB (0.55) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105727593-B | The preparation and application of the organic polymer liquid phase solid chromatography column of hydrophily phosphocholine matrix | 暨南大学 | 2017-11-21 | — | — | CN | disclosed |
| CN-105727593-A | Preparation and application of organic polymer liquid phase integral chromatographic column of hydrophilic choline phosphoric acid matrix | 暨南大学 | 2016-07-06 | — | — | CN | disclosed |