Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.40 |
| ▸ | CHRM3 known ✓ | P20309 | 3/20 | 0.40 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.37 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498219 | 0.98 | TSHR (0.50) | THRBTSHRALDH1A1CHRM5CHRM1 | |
| Bromide SCHEMBL17536050 | 0.95 | TSHR (0.48) | THRBTSHRALDH1A1CHRM5CHRM1 | |
| Iodide SCHEMBL21253234 | 0.95 | TSHR (0.48) | THRBTSHRALDH1A1CHRM5CHRM1 | |
| SCHEMBL28044392 | 0.95 | TSHR (0.48) | THRBTSHRALDH1A1CHRM5CHRM1 | |
| Methacrylic Acid SCHEMBL28074139 | 0.92 | THRB (0.44) | THRBTSHRALDH1A1CHRM5CHRM1 | |
| SCHEMBL1262355 | 0.88 | TSHR (0.42) | THRBTSHRALDH1A1CHRM5CHRM1 | |
| SCHEMBL11760936 | 0.83 | TSHR (0.39) | THRBTSHRALDH1A1POLBGALR3 | |
| SCHEMBL4937680 | 0.83 | TSHR (0.39) | THRBTSHRALDH1A1GALR3 | |
| Hydrochloric Acid SCHEMBL555449 | 0.81 | THRB (0.50) | THRBTSHRALDH1A1CHRM5CHRM1 | |
| SCHEMBL5145800 | 0.80 | THRB (0.42) | THRBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107614265-A | The method and system of electrically conductive ink in-situ sintering | 斯特拉塔西斯公司 | 2018-01-19 | — | — | CN | claimed |
| CN-103262319-B | Vacuum chamber method to form polymer coatings on porous support | GEN ELECTRIC | 2015-07-22 | — | — | CN | claimed |
| US-20250360491-A1 | STATIONARY PHASE FOR CHROMATOGRAPHY | DAICEL CORPORATION (JP) | 2025-11-27 | — | — | US | disclosed |
| US-12403452-B2 | Stationary phase for chromatography | DAICEL CORPORATION (JP) | 2025-09-02 | — | — | US | disclosed |
| CN-119708389-A | Thickening synergist applicable to glyphosate compound water aqua and preparation method thereof | 威尔（福建）生物有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-118240135-A | Emulsion polymer for low-permeability heavy oil reservoir pressure flooding and preparation method thereof | 中国石油化工股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| US-20210252479-A1 | STATIONARY PHASE FOR CHROMATOGRAPHY | DAICEL CORPORATION (JP) | 2021-08-19 | — | — | US | disclosed |
| EP-3845307-A1 | STATIONARY PHASE FOR CHROMATOGRAPHY | Daicel Corporation (JP) | 2021-07-07 | — | — | EP | disclosed |
| CN-112638519-A | Stationary phase for chromatography | 株式会社大赛璐 | 2021-04-09 | — | — | CN | disclosed |
| EP-3302444-B1 | PHARMACEUTICAL OR NUTRACEUTICAL COMPOSITION WITH RESISTANCE AGAINST THE INFLUENCE OF ETHANOL | EVONIK OPERATIONS GMBH (DE) | 2020-09-23 | — | — | EP | disclosed |
| EP-2992909-B1 | METAL MEDICAL DEVICE | SUMITOMO RUBBER IND (JP) | 2019-02-13 | — | — | EP | disclosed |
| US-10092680-B2 | Metal medical device | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2018-10-09 | — | — | US | disclosed |
| CN-107614265-A | The method and system of electrically conductive ink in-situ sintering | 斯特拉塔西斯公司 | 2018-01-19 | — | — | CN | disclosed |
| WO-2017135938-A1 | ENHANCING PROPPED COMPLEX FRACTURE NETWORKS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-08-10 | — | — | WO | disclosed |
| EP-2992909-A1 | METAL MEDICAL DEVICE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2016-03-09 | — | — | EP | disclosed |
| US-20160058919-A1 | METAL MEDICAL DEVICE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2016-03-03 | — | — | US | disclosed |
| CN-103262319-B | Vacuum chamber method to form polymer coatings on porous support | GEN ELECTRIC | 2015-07-22 | — | — | CN | disclosed |
| US-4726906-A | UNSATURATED CARBOXYLIC ACID, UNSATURATED SULFONIC ACID, UNSATURATED CATIONIC MONOMER | CALGON CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4652623-A | Polymers for use as filtration control aids in drilling muds | CALGON CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |