Biphenyl

Biphenyl

SCHEMBL28087429

C1CCC(C2CCCCC2)CC1.CCOC(C)=O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.61
LMNA P02545 1/20 0.61
HSD17B10 Q99714 1/20 0.61
THRB P10828 1/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TSHR P16473 4/20 0.40
NPSR1 Q6W5P4 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.38
CCR1 P32246 1/20 0.38
EPHX1 P07099 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL3810832 0.98 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10THRBATM
Cyclohexane SCHEMBL7396484 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10THRBATM
Cyclohexane SCHEMBL338160 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10THRBATM
Cyclohexane SCHEMBL15635357 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10THRBATM
Cyclohexane SCHEMBL855765 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10THRBATM
Cyclohexane SCHEMBL509143 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10THRBATM
Cyclohexane SCHEMBL416739 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10THRBATM
Cyclohexane SCHEMBL232777 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10THRBATM
Cyclohexane SCHEMBL5908851 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10THRBATM
Cyclohexane SCHEMBL1172967 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10THRBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105732756-B A kind of purification process of fat-soluble dexamethasone derivative 首都师范大学 2017-11-03 CN claimed
CN-105732756-A Purification method of fat-soluble dexamethasone derivatives 首都师范大学 2016-07-06 CN disclosed