Sugi Predict

Sugi Predict / Compounds / Cyclohexane

Cyclohexane

Cyclohexane

SCHEMBL338160

C1CCCCC1.C1CCCCC1.C1CCCCC1.C1CCCCC1.C1CCCCC1.C1CCCCC1.C1CCCCC1.C1CCCCC1.CCOC(C)=O.CCOC(C)=O

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.82
▸ LMNA P02545 2/20 0.82
▸ HSD17B10 Q99714 1/20 0.82
▸ TSHR P16473 1/20 0.50
▸ ALOX15 P16050 1/20 0.46
▸ MGAM O43451 1/20 0.46
▸ GAA P10253 1/20 0.46
▸ SI P14410 1/20 0.46
▸ MGAM2 Q2M2H8 1/20 0.46
▸ SOAT1 P35610 1/20 0.46
▸ TRPA1 O75762 1/20 0.42
▸ GLO1 Q04760 1/20 0.41
▸ CA12 O43570 2/20 0.39
▸ CA1 P00915 2/20 0.39
▸ CA2 P00918 2/20 0.39
▸ CA9 Q16790 2/20 0.39
▸ PGR P06401 1/20 0.39
▸ CHRM2 P08172 1/20 0.39
▸ CHRM4 P08173 1/20 0.39
▸ HTR1A P08908 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL510060 1.00 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL232773 1.00 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL15635357 1.00 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL232777 1.00 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL5908851 1.00 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL855765 1.00 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL1172967 1.00 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL416739 1.00 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL509143 1.00 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL7396484 1.00 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023175121-A1 METHOD FOR RADICAL POLYMERISATION OF THIONOLACTIDES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-09-21 — — WO disclosed
EP-4227307-A1 PYRAZOLOPYRAZINE COMPOUNDS AS SHP2 INHIBITORS Genzyme Corporation (US) 2023-08-16 — — EP disclosed
WO-2023114954-A1 PYRAZOLOPYRAZINE COMPOUNDS AS SHP2 INHIBITORS GENZYME CORPORATION (US) 2023-06-22 — — WO disclosed
CN-115715286-A BCL-2 family protein modulating compounds for cancer treatment 弗朗索瓦巴克莱斯对抗癌症中心地区 2023-02-24 — — CN disclosed
CN-108707140-B Protease C inhibitors 勃林格殷格翰国际有限公司 2022-07-22 — — CN disclosed
US-20210300935-A1 PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS Nerviano Medical Sciences, S.R.L. (IT) 2021-09-30 — — US disclosed
CN-113164660-A Immobilized biological entities 卡梅达股份公司 2021-07-23 — — CN disclosed
EP-2280983-B9 C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY TFCHEM (FR) 2021-06-09 — — EP disclosed
US-20210163484-A1 METHOD FOR SYNTHESIZING DIVERSELY SUBSTITUTED PURINES UNIVERSITÉ GRENOBLE ALPES (FR) 2021-06-03 — — US disclosed
EP-3619211-A1 METHOD FOR SYNTHESIZING DIVERSELY SUBSTITUTED PURINES Université Grenoble Alpes (FR) 2020-03-11 — — EP disclosed
US-5149696-A Antiestrogens ROUSSEL UCLAF (FR) 1992-09-22 — — US disclosed
WO-1992015587-A1 ANTIBACTERIAL CONDENSED CARBAPENEMES GLAXO S.P.A. (IT) 1992-09-17 — — WO disclosed
EP-0502464-A1 Antibacterial condensed carbapenemes GLAXO S.p.A. (IT) 1992-09-09 — — EP disclosed
US-5145980-A OXIME ETHERS, AND FUNGICIDES CONTAINING SAME BASF AKTIENGESELLSCHAFT (DE) 1992-09-08 — — US disclosed
US-5086047-A Controlling estrogen production; breast cancer ROUSSEL UCLAF, DEPARTMENT DES BREVETS (FR) 1992-02-04 — — US disclosed
EP-0416953-A2 10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo[7.2.0.0.3,8]undec-2-ene-2-carboxylic acid derivatives GLAXO S.p.A. (IT) 1991-03-13 — — EP disclosed
US-4988684-A Steroids for the inhibition of aromatase for the treatment of cancer ROUSSEL UCLAF (FR) 1991-01-29 — — US disclosed
CN-1038283-A Amino acid ester, their preparation method, the medicine that contains them and application thereof HOECHST AG (DE) 1989-12-27 — — CN disclosed
US-4753932-A ANTIGLUCOCORTICOID ACTIVITY ROUSSEL UCLAF (FR) 1988-06-28 — — US disclosed
US-4097494-A Novel cyclopentanones ROUSSEL UCLAF (FR) 1978-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210300935-A1 PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS MAP3K5, MAP3K9, MAP4K2 ALDH1A1 3081/4885LMNA 2710/4885HSD17B10 4523/4885
US-20210163484-A1 METHOD FOR SYNTHESIZING DIVERSELY SUBSTITUTED PURINES PNP, UMPS, NUDT1 ALDH1A1 698/4885LMNA 868/4885HSD17B10 3399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.