Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 11/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28650599 | 0.88 | MEN1 (0.66) | LMNAMEN1KMT2AMAPK1MAOB | |
| SCHEMBL28087550 | 0.85 | MAOB (0.61) | LMNAMEN1KMT2AMAPK1MAOB | |
| SCHEMBL6260303 | 0.79 | LMNA (0.61) | LMNAMEN1KMT2AMAPK1MAOB | |
| SCHEMBL28087485 | 0.76 | LMNA (0.61) | LMNAMEN1KMT2AMAPK1MAOB | |
| SCHEMBL28087551 | 0.75 | MEN1 (0.71) | LMNAMEN1KMT2AMAPK1MAOB | |
| SCHEMBL2777639 | 0.74 | KDM4E (0.66) | LMNAMEN1KMT2AMAPK1MAOB | |
| SCHEMBL3046337 | 0.72 | MAOB (0.61) | LMNAMEN1KMT2AMAPK1MAOB | |
| SCHEMBL4077096 | 0.72 | LMNA (0.57) | LMNAMEN1KMT2AMAPK1MAOB | |
| SCHEMBL25003552 | 0.72 | HPGD (0.79) | LMNAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL10585506 | 0.71 | SMN1; SMN2 (0.61) | LMNAMEN1KMT2AMAPK1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837544-B | A kind of organic nitrine synthesizes the new method of the ketones derivant of 3 amino chromene 2 with cumarin | 广西师范大学 | 2018-01-30 | — | — | CN | disclosed |
| CN-105837544-A | Novel method for synthesizing 3-aminobenzopyran-2-ketone derivative using organic azide and coumarin | 广西师范大学 | 2016-08-10 | — | — | CN | disclosed |