Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28087507 | 0.85 | LMNA (0.60) | MAOBACHEKMT2AMEN1LMNA | |
| SCHEMBL28650599 | 0.85 | MEN1 (0.66) | MAOBKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL31482350 | 0.84 | NPC1 (0.59) | MAOBACHEKMT2AMEN1LMNA | |
| SCHEMBL6260303 | 0.76 | LMNA (0.61) | MAOBACHEKMT2AMEN1LMNA | |
| SCHEMBL830092 | 0.73 | GAA (0.53) | MAOBACHEKMT2ANPC1RAB9A | |
| SCHEMBL1370027 | 0.73 | KMT2A (0.63) | MAOBKMT2AMEN1LMNANPC1 | |
| SCHEMBL8363323 | 0.73 | ALDH1A1 (0.60) | MAOBACHEKMT2AMEN1LMNA | |
| SCHEMBL28087485 | 0.73 | LMNA (0.61) | MAOBACHEKMT2AMEN1LMNA | |
| SCHEMBL28688171 | 0.73 | MAOB (0.63) | MAOBACHEKMT2AMEN1LMNA | |
| SCHEMBL18305555 | 0.72 | KMT2A (0.53) | MAOBACHEKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837544-B | A kind of organic nitrine synthesizes the new method of the ketones derivant of 3 amino chromene 2 with cumarin | 广西师范大学 | 2018-01-30 | — | — | CN | disclosed |
| CN-105837544-A | Novel method for synthesizing 3-aminobenzopyran-2-ketone derivative using organic azide and coumarin | 广西师范大学 | 2016-08-10 | — | — | CN | disclosed |