SCHEMBL28087757

SCHEMBL28087757

NNC(=O)c1cccc(-c2ccccn2)c1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 3/20 0.59
PRMT5 O14744 4/20 0.53
WDR77 Q9BQA1 4/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
SCN9A Q15858 3/20 0.51
SIRT2 Q8IXJ6 2/20 0.50
CNR1 P21554 1/20 0.50
SCN5A Q14524 2/20 0.48
CTSL P07711 1/20 0.48
CTSB P07858 1/20 0.48
CTSS P25774 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
AOC2 O75106 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27824565 0.85 TRPV1 (0.58) KDM4EALDH1A1MEN1KMT2A
SCHEMBL11185348 0.85 KDM4E (0.49) KAT6AKDM4EALDH1A1SCN9ASIRT2
SCHEMBL28327925 0.85 KDM4E (0.58) KAT6AKDM4EALDH1A1SIRT2MEN1
SCHEMBL17239451 0.84 KAT6A (0.59) KAT6APRMT5WDR77KDM4ESCN9A
SCHEMBL13886161 0.83 CDK8 (0.56) KAT6APRMT5WDR77SCN9ASIRT2
SCHEMBL28254875 0.82 ALDH1A1 (0.68) KAT6AKDM4EALDH1A1HDAC8AOC2
SCHEMBL25700071 0.82 ALDH1A1 (0.68) KAT6AKDM4EALDH1A1HDAC8AOC2
SCHEMBL8700012 0.82 KAT6A (0.54) KAT6APRMT5WDR77SCN9ASIRT2
SCHEMBL30036208 0.81 CHEK2 (0.57) KAT6AKDM4ECNR1
SCHEMBL167080 0.81 CHEK2 (0.57) KAT6AKDM4ECNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106588993-A Iridium complex, preparation method thereof and light-emitting device using the same 瑞声光电科技(常州)有限公司 2017-04-26 CN claimed
CN-106432347-A Iridium complexes, preparation method thereof and electroluminescent device using iridium complexes 瑞声光电科技(常州)有限公司 2017-02-22 CN claimed
CN-106432351-A Iridium complexes and preparation method thereof and electroluminescent devices using iridium complexes 瑞声光电科技(常州)有限公司 2017-02-22 CN claimed
CN-106397494-A Iridium complex as well as preparation method and electroluminescence device with iridium complex 瑞声光电科技(常州)有限公司 2017-02-15 CN claimed
CN-106397490-A Iridium complex as well as preparation method thereof and electroluminescent device applied to iridium complex 瑞声光电科技(常州)有限公司 2017-02-15 CN claimed
CN-106188148-A The luminescent device of complex of iridium and its preparation method and application complex of iridium 瑞声光电科技(常州)有限公司 2016-12-07 CN claimed
CN-106117272-A The electroluminescent device of this complex of iridium of complex of iridium and its preparation method and application 瑞声光电科技(常州)有限公司 2016-11-16 CN claimed
CN-106117273-A The electroluminescent device of complex of iridium and its preparation method and application complex of iridium 瑞声光电科技(常州)有限公司 2016-11-16 CN claimed
CN-106046060-A Iridium complex and preparation method thereof as well as electroluminescent device applying iridium complex 瑞声光电科技(常州)有限公司 2016-10-26 CN claimed
CN-106432346-A Iridium complex, preparation method thereof and electroluminescent device applying same 瑞声光电科技(常州)有限公司 2017-02-22 CN disclosed
CN-106432347-A Iridium complexes, preparation method thereof and electroluminescent device using iridium complexes 瑞声光电科技(常州)有限公司 2017-02-22 CN disclosed
CN-106432351-A Iridium complexes and preparation method thereof and electroluminescent devices using iridium complexes 瑞声光电科技(常州)有限公司 2017-02-22 CN disclosed
CN-106432350-A Iridium complex, preparation method thereof and electroluminescent device applying iridium complex 瑞声光电科技(常州)有限公司 2017-02-22 CN disclosed
CN-106432349-A Iridium complex, preparation method thereof and electroluminescent device employing iridium complex 瑞声光电科技(常州)有限公司 2017-02-22 CN disclosed
CN-106117271-A The electroluminescent device of this complex of iridium of complex of iridium and its preparation method and application 瑞声光电科技(常州)有限公司 2016-11-16 CN disclosed
CN-106117272-A The electroluminescent device of this complex of iridium of complex of iridium and its preparation method and application 瑞声光电科技(常州)有限公司 2016-11-16 CN disclosed
CN-106117273-A The electroluminescent device of complex of iridium and its preparation method and application complex of iridium 瑞声光电科技(常州)有限公司 2016-11-16 CN disclosed
CN-106046060-A Iridium complex and preparation method thereof as well as electroluminescent device applying iridium complex 瑞声光电科技(常州)有限公司 2016-10-26 CN disclosed
CN-104370887-B The synthetic method of double [3-(N-carbazyl) phenyl] pyridine compounds and their of 2,6- 北京阿格蕾雅科技发展有限公司 2016-08-24 CN disclosed
CN-104370887-B The synthetic method of double [3-(N-carbazyl) phenyl] pyridine compounds and their of 2,6- 北京阿格蕾雅科技发展有限公司 2016-08-24 CN disclosed