Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 3/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8703710 | 0.99 | KAT6A (0.53) | KAT6ASCN9APRMT5WDR77SIRT2 | |
| SCHEMBL8706110 | 0.85 | ROCK1 (0.41) | KAT6ASIRT2 | |
| Hydrochloric Acid SCHEMBL8700357 | 0.84 | ROCK1 (0.40) | KAT6ASIRT2 | |
| SCHEMBL5175529 | 0.83 | HDAC8 (0.62) | KAT6AHDAC8 | |
| Hydrochloric Acid SCHEMBL8705323 | 0.82 | HDAC8 (0.60) | KAT6AHDAC8 | |
| SCHEMBL28087757 | 0.82 | KAT6A (0.59) | KAT6ASCN9APRMT5WDR77SIRT2 | |
| SCHEMBL21884657 | 0.81 | P2RX7 (0.44) | KAT6ACHEK2HDAC8 | |
| SCHEMBL167080 | 0.80 | CHEK2 (0.57) | KAT6ACNR1CHEK2 | |
| SCHEMBL30036208 | 0.80 | CHEK2 (0.57) | KAT6ACNR1CHEK2 | |
| SCHEMBL8690577 | 0.80 | KAT6A (0.42) | KAT6ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |