Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MAX | P61244 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28087917 | 0.86 | PTPN1 (0.44) | HDAC7PTPN1FOLH1PTPN2PTPN6 | |
| SCHEMBL22227470 | 0.85 | BRS3 (0.48) | BRS3LTB4R2 | |
| SCHEMBL23927634 | 0.80 | RARB (0.43) | PTGS1PTGS2 | |
| SCHEMBL23927583 | 0.77 | LCK (0.39) | PTGS1PTGS2 | |
| SCHEMBL29100387 | 0.76 | BACE1 (0.64) | HDAC7PTPN1FOLH1PTPN2PTPN6 | |
| SCHEMBL9509918 | 0.76 | METAP2 (0.53) | HDAC7PTPN1FOLH1PTPN2PTPN6 | |
| SCHEMBL4368156 | 0.76 | FOLH1 (0.58) | PTPN1FOLH1PTPN2PTPN6MYC | |
| SCHEMBL6775461 | 0.75 | PTPN1 (0.56) | HDAC7PTPN1FOLH1PTPN2PTPN6 | |
| SCHEMBL22227471 | 0.74 | LTB4R2 (0.49) | BRS3LTB4R2 | |
| SCHEMBL23927696 | 0.73 | FOLH1 (0.50) | FOLH1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105745187-A | Compounds useful in the treatment of neoplastic diseases | 科隆大学 | 2016-07-06 | — | — | CN | claimed |
| CN-105745187-B | For treating the compound of tumor disease | 科隆大学 | 2019-04-30 | — | — | CN | disclosed |
| CN-105745187-A | Compounds useful in the treatment of neoplastic diseases | 科隆大学 | 2016-07-06 | — | — | CN | disclosed |