Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.65 |
| ▸ | MAOA | P21397 | 3/20 | 0.65 |
| ▸ | GABRP | O00591 | 4/20 | 0.62 |
| ▸ | GABRD | O14764 | 4/20 | 0.62 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.62 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.62 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.62 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.62 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.62 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.62 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.62 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.62 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.62 |
| ▸ | GABRE | P78334 | 4/20 | 0.62 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.62 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.62 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.62 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29811226 | 1.00 | MAOB (0.65) | MAOBMAOAGABRPGABRDGABRA1 | |
| SCHEMBL20471704 | 0.86 | GABRP (0.58) | MAOBMAOAGABRPGABRDGABRA1 | |
| SCHEMBL4448895 | 0.81 | MAOB (0.68) | MAOBMAOAGABRPGABRDGABRA1 | |
| SCHEMBL31105656 | 0.81 | MAOB (0.71) | MAOBMAOAGABRPGABRDGABRA1 | |
| SCHEMBL731363 | 0.81 | MAOB (0.71) | MAOBMAOAGABRPGABRDGABRA1 | |
| SCHEMBL12369503 | 0.80 | MAOB (0.69) | MAOBMAOAGABRPGABRDGABRA1 | |
| SCHEMBL16719694 | 0.79 | GABRP (0.48) | MAOBMAOAGABRPGABRDGABRA1 | |
| SCHEMBL4111056 | 0.79 | MAOB (0.65) | MAOBMAOAALOX5PTPRCPTPN1 | |
| SCHEMBL6676481 | 0.79 | MAOB (0.65) | MAOBMAOAALOX5PTPRCPTPN1 | |
| SCHEMBL31290937 | 0.79 | MAOB (0.65) | MAOBMAOAGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751882-B | Synthesis method of benzofuran | 南京工业大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-114751882-A | Synthetic method of benzofuran | 南京工业大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-108440515-A | Substituted benzofuranyl and benzoxazole based compound and application thereof | 卡尔约药物治疗公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-105492437-B | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof | 卡尔约药物治疗公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-105837539-A | Method for substituting 2-site aryl for 3-site fluoro of benzofuran ring | 复旦大学 | 2016-08-10 | — | — | CN | disclosed |