Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25241611 | 0.80 | HPRT1 (0.49) | HPRT1ALDH1A1TDP1ABCC8KCNJ11 | |
| SCHEMBL4958866 | 0.77 | ALDH1A1 (0.36) | HPRT1ALDH1A1TDP1ABCC8KCNJ11 | |
| SCHEMBL1224154 | 0.76 | TSHR (0.41) | ALDH1A1TDP1TSHRSMN1; SMN2PKM | |
| SCHEMBL273394 | 0.76 | TSHR (0.41) | ALDH1A1TDP1TSHRSMN1; SMN2PKM | |
| SCHEMBL10941016 | 0.74 | TSHR (0.39) | ALDH1A1TDP1TSHRMAPTNPC1 | |
| SCHEMBL4928732 | 0.74 | TDP1 (0.40) | ALDH1A1TDP1TSHRSMN1; SMN2PKM | |
| SCHEMBL4928738 | 0.74 | TDP1 (0.40) | ALDH1A1TDP1TSHRSMN1; SMN2PKM | |
| SCHEMBL28021446 | 0.71 | HPRT1 (0.44) | HPRT1ALDH1A1TDP1ABCC8KCNJ11 | |
| SCHEMBL4923849 | 0.71 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRCYP3A4MAPT | |
| SCHEMBL27322672 | 0.71 | MEN1 (0.41) | ALDH1A1TDP1TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858944-B | Delivery of particles | 宝洁公司 | 2016-08-24 | — | — | CN | disclosed |