Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12483903 | 0.77 | TET2 (0.44) | ABCG2CCR1CCR5CCR8KDM4E | |
| SCHEMBL28012715 | 0.77 | ABCG2 (0.37) | ABCG2CCR1CCR5CCR8NPC1 | |
| SCHEMBL7082437 | 0.77 | ABCG2 (0.37) | ABCG2CCR1CCR5CCR8 | |
| SCHEMBL25519639 | 0.77 | CCR1 (0.67) | ABCG2CCR1CCR5CCR8KDM4E | |
| SCHEMBL12483271 | 0.77 | ABCG2 (0.40) | ABCG2CCR1CCR5CCR8KDM4E | |
| SCHEMBL29801578 | 0.77 | TET2 (0.44) | ABCG2CCR1CCR5CCR8KDM4E | |
| SCHEMBL6698154 | 0.73 | ABCG2 (0.38) | ABCG2CCR1CCR5CCR8 | |
| SCHEMBL25526981 | 0.73 | ABCG2 (0.45) | ABCG2CCR1CCR5CCR8 | |
| SCHEMBL6698156 | 0.73 | ABCG2 (0.38) | ABCG2CCR1CCR5CCR8L3MBTL1 | |
| SCHEMBL29940529 | 0.72 | PSMD14 (0.53) | ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105906563-B | The synthetic method of 7,8- difluoro-quinoline -3- formic acid | 苏州康润医药有限公司 | 2019-01-22 | — | — | CN | disclosed |
| CN-105906563-A | Synthesis method of 7, 8-difluoroquinoline-3-formic acid | 苏州康润医药有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-104447543-B | Synthesis method of 3-amino-7, 8-difluoroquinoline and intermediate thereof | 苏州康润医药有限公司 | 2016-08-24 | — | — | CN | disclosed |