Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28088571

C1CCOC1.CC(Cl)Cl.ClCCCl

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dioxane SCHEMBL28096714 0.88 ALDH1A1 (0.38) ALDH1A1TSHR
Tetrahydrofuran SCHEMBL2975678 0.88
SCHEMBL3093207 0.85 ALDH1A1 (0.53) ALDH1A1TSHR
Tetrahydrofuran SCHEMBL28820736 0.85
Tetrahydrofuran SCHEMBL5106977 0.85
Tetrahydrofuran SCHEMBL27923803 0.82 ALDH1A1 (0.57) ALDH1A1TSHR
Tetrahydrofuran SCHEMBL3618483 0.82 ALDH1A1 (0.57) ALDH1A1TSHR
Cyclopentane SCHEMBL28201515 0.78 TSHR (0.46) ALDH1A1TSHRMEN1KMT2A
Cycloheptane SCHEMBL28142512 0.78 TSHR (0.46) ALDH1A1TSHRMEN1KMT2A
Tetrahydrofuran SCHEMBL28184579 0.77 ALDH1A1 (0.50) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106967094-B The manufacturing method of hydrazine compound, the manufacturing method of optically anisotropic body and polymerizable compound 日本瑞翁株式会社 2019-11-15 CN disclosed
CN-110392703-A Polymerizable compound and its manufacturing method, polymerizable composition, polymerizable composition, macromolecule, optical film, optically anisotropic body, polarizing film, display device, antireflection film and compound and its application method 日本瑞翁株式会社 2019-10-29 CN disclosed
CN-110382471-A Polymerizable compound, polymerizable liquid crystal mixture, macromolecule, optical film, optically anisotropic body, polarizing film, display device, antireflection film and compound 日本瑞翁株式会社 2019-10-25 CN disclosed
CN-110347018-A Electrophtography photosensor, handle box, image forming apparatus 富士施乐株式会社 2019-10-18 CN disclosed
CN-110099896-A Polymerizable compound, polymerizable liquid crystal mixture, macromolecule, optical film, optically anisotropic body, polarizing film, display device, antireflection film and compound 日本瑞翁株式会社 2019-08-06 CN disclosed
CN-110088152-A The manufacturing method of mixture, macromolecule, optical film, optically anisotropic body, polarizing film, display device and antireflection film and mixture 日本瑞翁株式会社 2019-08-02 CN disclosed
CN-106278943-B Optical thin film, polymerizable compound, polymerizable composition, polymerizable composition, macromolecule, optically anisotropic body and hydrazine compound 日本瑞翁株式会社 2019-07-30 CN disclosed
CN-110072854-A Polymerizable compound, mixture, macromolecule, optical film, optically anisotropic body, polarizing film, display device and antireflection film 日本瑞翁株式会社 2019-07-30 CN disclosed
CN-110003008-A Mixture and compound 日本瑞翁株式会社 2019-07-12 CN disclosed
CN-109996780-A Polymerizable compound, polymerizable composition, polymerizable composition, macromolecule, optical film, optically anisotropic body, polarizing film, panel display apparatus, organic electroluminescence display device and method of manufacturing same, antireflection film and compound 日本瑞翁株式会社 2019-07-09 CN disclosed
CN-107963997-A The manufacture method of compound, mixture and polymerizable compound 日本瑞翁株式会社 2018-04-27 CN disclosed
CN-105452311-B Polymerizable compound, polymerizable composition, polymer, and optically anisotropic body 日本瑞翁株式会社 2018-01-16 CN disclosed
CN-107400100-A Polymerizable compound, mixture, composition, polymer, film, optically anisotropic body, polarizing plate, and display device 日本瑞翁株式会社 2017-11-28 CN disclosed
CN-106967094-A The manufacture method of hydrazine compound, the manufacture method of optically anisotropic body and polymerizable compound 日本瑞翁株式会社 2017-07-21 CN disclosed
CN-104995219-B Polymerizable compound, polymerizable composition, polymer, and optically anisotropic body 日本瑞翁株式会社 2017-06-06 CN disclosed
CN-106278943-A Optical thin film, polymerizable compound, polymerizable composition, polymerizable composition, macromolecule, optically anisotropic body and hydrazine compound 日本瑞翁株式会社 2017-01-04 CN disclosed
CN-104470957-B Polymerizable compound, polymerizable composition, polymer, and optically anisotropic body 日本瑞翁株式会社 2016-11-16 CN disclosed
CN-105960392-A Polymerizable compound, polymerizable composition, polymer, and optical isomer 日本瑞翁株式会社 2016-09-21 CN disclosed
CN-105940017-A Polymerizable compound, polymerizable composition, polymer, and optically anisotropic body 日本瑞翁株式会社 2016-09-14 CN disclosed
CN-103492363-B Polymerizable compound, polymerizable composition, polymer, and optically anisotropic body 日本瑞翁株式会社 2016-08-24 CN disclosed